TRIM11

Gene Symbol TRIM11
Entrez Gene 81559
Alt Symbol BIA1, RNF92
Species Human
Gene Type protein-coding
Description tripartite motif containing 11
Other Description E3 ubiquitin-protein ligase TRIM11|RING finger protein 92|tripartite motif-containing 11|tripartite motif-containing protein 11
Swissprots B3KUS3 Q8NCA6 Q96F44 Q9C022 Q5VSU1 B4DX88 A6NKE2 B2RB82
Accessions EAW69871 Q96F44 AF220125 AAG53498 AF327056 AAM63957 AK074866 BAC11254 AK097825 BAG53535 AK226119 AK301859 BAG63300 AK314539 BAG37129 AL360165 BC011629 AAH11629 BC069227 AAH69227 EU447015 ABZ92544 XM_011544285 XP_011542587 NM_145214 NP_660215
Function E3 ubiquitin-protein ligase that promotes the degradation of insoluble ubiquitinated proteins, including insoluble PAX6, poly-Gln repeat expanded HTT and poly-Ala repeat expanded ARX. Mediates PAX6 ubiquitination leading to proteasomal degradation, thereby modulating cortical neurogenesis. May also inhibit PAX6 transcriptional activity, possibly in part by preventing the binding of PAX6 to its consensus sequences. May contribute to the regulation of the intracellular level of HN (humanin) or HN-containing proteins through the proteasomal degradation pathway. Mediates MED15 ubiquitination leading to proteasomal degradation. May contribute to the innate restriction of retroviruses. Upon overexpression, reduces HIV-1 and murine leukemia virus infectivity, by suppressing viral gene expression. Antiviral activity depends on a functional E3 ubiquitin-protein ligase domain. May regulate TRIM5 turnover via the proteasome pathway, thus counteracting the TRIM5-mediated cross-species restriction
Subcellular Location Cytoplasm. Nucleus.
Tissue Specificity Ubiquitous.

TRIM11 CRISPR/Cas9 KO Plasmid (h) - sc-408290 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRIM11 HDR Plasmid (h) - sc-408290-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRIM11 Double Nickase Plasmid (h) - sc-408290-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRIM11 Double Nickase Plasmid (h2) - sc-408290-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRIM11 CRISPR Activation Plasmid (h) - sc-408290-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRIM11 CRISPR Activation Plasmid (h2) - sc-408290-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRIM11 Lentiviral Activation Particles (h) - sc-408290-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRIM11 Lentiviral Activation Particles (h2) - sc-408290-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRIM11 siRNA (h) - sc-76734 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TRIM11 shRNA Plasmid (h) - sc-76734-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TRIM11 shRNA (h) Lentiviral Particles - sc-76734-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Trim11 RNAi - H00081559-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN21952 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08314 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr08314

TRIM11 siRNA (Human) - CRJ2998 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TRIM11 - MBS8237553 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TRIM11 (NM_145214.2) - SHH434376 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human TRIM11(NM_145214.2) - SHL093194 from Creative biogene

Category siRNA
Species Reactivities Human

TRIM11 shRNA Plasmid (Human) - CHJ2998 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TRIM11 miRNA 3'UTR clone - MiUTR1H-10714 from Creative biogene

Species Reactivities Human
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