| Gene Symbol | ASAP2 |
|---|---|
| Entrez Gene | 8853 |
| Alt Symbol | AMAP2, CENTB3, DDEF2, PAG3, PAP, Pap-alpha, SHAG1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 |
| Other Description | PYK2 C terminus-associated protein|arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2|centaurin, beta 3|development and differentiation enhancing factor 2|development and differentiation-enhancing factor 2|paxillin-associated protein with ARF GAP activity 3|pyk2 C-terminus-associated protein |
| Swissprots | D6W4Y8 O43150 |
| Accessions | AAY14856 AAY14904 AAY24112 EAX01002 EAX01003 EAX01004 EAX01005 EAX01006 O43150 AA918883 AB007860 BAA23696 AK091121 BAC03588 AK123185 AK124900 BC063308 AAH63308 XM_006711898 XP_006711961 XM_006711901 XP_006711964 XM_006711902 XP_006711965 XM_011510403 XP_011508705 XM_011510404 XP_011508706 XM_011510405 XP_011508707 XM_011510406 XP_011508708 XM_011510407 XP_011508709 XM_011510408 XP_011508710 XM_011510409 XP_011508711 NM_001135191 NP_001128663 NM_003887 NP_003878 |
| Function | Activates the small GTPases ARF1, ARF5 and ARF6. Regulates the formation of post-Golgi vesicles and modulates constitutive secretion. Modulates phagocytosis mediated by Fc gamma receptor and ARF6. Modulates PXN recruitment to focal contacts and cell migration. {ECO:0000269|PubMed:10022920, ECO:0000269|PubMed:10749932, ECO:0000269|PubMed:11304556}. |
| Subcellular Location | Cytoplasm. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Note=Colocalizes with F-actin and ARF6 in phagocytic cups. |
| Tissue Specificity | Detected in heart, brain, placenta, kidney, monocytes and pancreas. {ECO:0000269|PubMed:10022920}. |
| Top Pathways | Fc gamma R-mediated phagocytosis, Endocytosis |
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 (ASAP2), Human, ELISA Kit - E01A1697 from ARP American Research Products
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Arf GAP with SH3 domain, ANK repeat and PH domain containing protein 2 (ASAP2), ELISA Kit - MBS7203737 from MyBioSource
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Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 (ASAP2), ELISA Kit - MBS7203605 from MyBioSource
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Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 (ASAP2), ELISA Kit - MBS7244834 from MyBioSource
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Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 (ASAP2), ELISA Kit - MBS7212580 from MyBioSource
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Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 (ASAP2), ELISA Kit - MBS7247146 from MyBioSource
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Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 (ASAP2), ELISA Kit - MBS7229277 from MyBioSource
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Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 (ASAP2), ELISA Kit - MBS7226986 from MyBioSource
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Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 (ASAP2), ELISA Kit - MBS7206057 from MyBioSource
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Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 (ASAP2), ELISA Kit - MBS7228845 from MyBioSource
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Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 (ASAP2), ELISA Kit - MBS7216823 from MyBioSource
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Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 (ASAP2), ELISA Kit - MBS7214062 from MyBioSource
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Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 (ASAP2), ELISA Kit - MBS7243006 from MyBioSource
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Human ASAP2 ELISA Kit - E003576 from Biobool
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