ASAP2

Gene Symbol ASAP2
Entrez Gene 8853
Alt Symbol AMAP2, CENTB3, DDEF2, PAG3, PAP, Pap-alpha, SHAG1
Species Human
Gene Type protein-coding
Description ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
Other Description PYK2 C terminus-associated protein|arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2|centaurin, beta 3|development and differentiation enhancing factor 2|development and differentiation-enhancing factor 2|paxillin-associated protein with ARF GAP activity 3|pyk2 C-terminus-associated protein
Swissprots D6W4Y8 O43150
Accessions AAY14856 AAY14904 AAY24112 EAX01002 EAX01003 EAX01004 EAX01005 EAX01006 O43150 AA918883 AB007860 BAA23696 AK091121 BAC03588 AK123185 AK124900 BC063308 AAH63308 XM_006711898 XP_006711961 XM_006711901 XP_006711964 XM_006711902 XP_006711965 XM_011510403 XP_011508705 XM_011510404 XP_011508706 XM_011510405 XP_011508707 XM_011510406 XP_011508708 XM_011510407 XP_011508709 XM_011510408 XP_011508710 XM_011510409 XP_011508711 NM_001135191 NP_001128663 NM_003887 NP_003878
Function Activates the small GTPases ARF1, ARF5 and ARF6. Regulates the formation of post-Golgi vesicles and modulates constitutive secretion. Modulates phagocytosis mediated by Fc gamma receptor and ARF6. Modulates PXN recruitment to focal contacts and cell migration. {ECO:0000269|PubMed:10022920, ECO:0000269|PubMed:10749932, ECO:0000269|PubMed:11304556}.
Subcellular Location Cytoplasm. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Note=Colocalizes with F-actin and ARF6 in phagocytic cups.
Tissue Specificity Detected in heart, brain, placenta, kidney, monocytes and pancreas. {ECO:0000269|PubMed:10022920}.
Top Pathways Fc gamma R-mediated phagocytosis, Endocytosis

DDEF2 CRISPR/Cas9 KO Plasmid (h) - sc-403676 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DDEF2 HDR Plasmid (h) - sc-403676-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DDEF2 Double Nickase Plasmid (h) - sc-403676-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DDEF2 Double Nickase Plasmid (h2) - sc-403676-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DDEF2 CRISPR Activation Plasmid (h) - sc-403676-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DDEF2 CRISPR Activation Plasmid (h2) - sc-403676-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DDEF2 Lentiviral Activation Particles (h) - sc-403676-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DDEF2 Lentiviral Activation Particles (h2) - sc-403676-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DDEF2 siRNA (h) - sc-41694 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DDEF2 shRNA Plasmid (h) - sc-41694-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DDEF2 shRNA (h) Lentiviral Particles - sc-41694-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PAG3 RNAi - H00008853-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU114761 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

MISSION® esiRNA - EHU024461 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3564 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3564 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR11512 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr11512

ASAP2 siRNA (Human) - CRH5846 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ASAP2 - MBS8232959 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ASAP2 (NM_003887.2) - SHH241106 from Creative biogene

Category siRNA
Species Reactivities Human

Human ASAP2 siRNA - orb266348 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ASAP2 shRNA Plasmid (Human) - CHH5846 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ASAP2 miRNA 3'UTR clone - MiUTR4H-TG00546 from Creative biogene

Species Reactivities Human
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