ASAP2

Gene Symbol ASAP2
Entrez Gene 8853
Alt Symbol AMAP2, CENTB3, DDEF2, PAG3, PAP, Pap-alpha, SHAG1
Species Human
Gene Type protein-coding
Description ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
Other Description PYK2 C terminus-associated protein|arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2|centaurin, beta 3|development and differentiation enhancing factor 2|development and differentiation-enhancing factor 2|paxillin-associated protein with ARF GAP activity 3|pyk2 C-terminus-associated protein
Swissprots D6W4Y8 O43150
Accessions AAY14856 AAY14904 AAY24112 EAX01002 EAX01003 EAX01004 EAX01005 EAX01006 O43150 AA918883 AB007860 BAA23696 AK091121 BAC03588 AK123185 AK124900 BC063308 AAH63308 XM_006711898 XP_006711961 XM_006711901 XP_006711964 XM_006711902 XP_006711965 XM_011510403 XP_011508705 XM_011510404 XP_011508706 XM_011510405 XP_011508707 XM_011510406 XP_011508708 XM_011510407 XP_011508709 XM_011510408 XP_011508710 XM_011510409 XP_011508711 NM_001135191 NP_001128663 NM_003887 NP_003878
Function Activates the small GTPases ARF1, ARF5 and ARF6. Regulates the formation of post-Golgi vesicles and modulates constitutive secretion. Modulates phagocytosis mediated by Fc gamma receptor and ARF6. Modulates PXN recruitment to focal contacts and cell migration. {ECO:0000269|PubMed:10022920, ECO:0000269|PubMed:10749932, ECO:0000269|PubMed:11304556}.
Subcellular Location Cytoplasm. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Note=Colocalizes with F-actin and ARF6 in phagocytic cups.
Tissue Specificity Detected in heart, brain, placenta, kidney, monocytes and pancreas. {ECO:0000269|PubMed:10022920}.
Top Pathways Fc gamma R-mediated phagocytosis, Endocytosis

Human PAG3 full length protein - ab160224 from Abcam

Category Protein
Source Wheat germ
Species Human
ab160224 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human PAG3 protein fragment - ab160225 from Abcam

Category Protein
Source Wheat germ
Species Human
ab160225 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Recombinant Human PAG3 Protein - H00008853-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human
Recombinant Human PAG3 Protein [H00008853-P01] - 12.5% SDS-PAGE Stained with Coomassie Blue.

Recombinant Human PAG3 Protein - H00008853-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

ASAP2-Antibody-C-term-Blocking-Peptide - BP17248b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

DDEF2 Blocking Peptide - abx161077 from Abbexa

Category Peptide
Species Human, Mouse, Rat

ASAP2 / DDEF2 - H00008853-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

ASAP2 / DDEF2 - H00008853-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

ASAP2 / DDEF2 - H00008853-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

ASAP2 / DDEF2 - H00008853-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

ASAP2 fusion protein - Ag5410 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

Recombinant Human ASAP2, His-tagged - ASAP2-9911H from Creative Biomart

Category Protein
Source E.coli
Species Human

Recombinant Human ASAP2, His-tagged - ASAP2-3618H from Creative Biomart

Category Protein
Source E. Coli or Yeast
Species Human

DDEF2 Blocking Peptide - CBP3576 from Cohesion Biosciences

Category Peptide
Prices $100.00, $300.00
Sizes 1 mg, 5 mg
Species Human, Mouse, Rat

Recombinant Human Arf-GAP with SH3 domain, ANK repeat and PH domain-containing p - CSB-YP002176HU CSB-EP002176HU CSB-BP002176HU CSB-MP002176HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2(ASAP2) ,partial, Recombinant Protein - MBS1110942 from MyBioSource

Category Protein
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

ASAP2 Peptide, Human - M34GP01007H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

DDEF2 peptide - orb234451 from Biorbyt

Category Peptide
Prices $247.00, $536.00
Sizes 1 mg, 5 mg
Search more