TRAF1

Gene Symbol TRAF1
Entrez Gene 7185
Alt Symbol EBI6, MGC:10353
Species Human
Gene Type protein-coding
Description TNF receptor-associated factor 1
Other Description Epstein-Bar virus-induced protein 6
Swissprots Q8NF13 Q13077 B4DJ77 Q658U1
Accessions CBX47545 EAW87479 Q13077 AK090468 BAC03449 AK295959 BAG58739 AK315476 BAG37860 AL832989 CAH56343 AW014547 BC024145 AAH24145 BT019408 AAV38215 HQ447750 ADQ32235 U19261 AAA62309 NM_001190945 NP_001177874 NM_001190947 NP_001177876 NM_005658 NP_005649
Function Adapter molecule that regulates the activation of NF- kappa-B and JNK. Plays a role in the regulation of cell survival and apoptosis. The heterotrimer formed by TRAF1 and TRAF2 is part of a E3 ubiquitin-protein ligase complex that promotes ubiquitination of target proteins, such as MAP3K14. The TRAF1/TRAF2 complex recruits the antiapoptotic E3 protein- ubiquitin ligases BIRC2 and BIRC3 to TNFRSF1B/TNFR2. {ECO:0000269|PubMed:10692572, ECO:0000269|PubMed:16323247, ECO:0000269|PubMed:18429822, ECO:0000269|PubMed:19287455, ECO:0000269|PubMed:19698991, ECO:0000269|PubMed:20385093}.
Top Pathways Small cell lung cancer, Herpes simplex infection, Viral carcinogenesis, Epstein-Barr virus infection, TNF signaling pathway

TRAF1 (1F3) Rat mAb - 4710 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rat
Clonality Monoclonal
Clone 1F3
Western blot analysis of extracts from Raji and SR cells, using TRAF1 (1F3) Rat mAb.

TRAF1 (45D3) Rabbit mAb - 4715 from Cell Signaling Technology

Prices $99.00, $246.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone 45D3
Western blot analysis of extracts from Raji and SR cells, using TRAF1 (45D3) Rabbit mAb.

TRAF1 Antibody - 4714 from Cell Signaling Technology

Host Rabbit
Clonality Polyclonal

TRAF1 (G-20) - sc-983 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
TRAF1 (G-20): sc-983. Immunofluorescence staining of methanol-fixed IB4-E25.22 cells showing cytoplasmic staining.

TRAF1 (H-125) - sc-1830 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
TRAF1 (H-125): sc-1830. Western blot analysis of TRAF1 expression in L75.11 (A), IB4 (B), WI 38 (C) and NTERA-2 cl.D1 (D) whole cell lysates.

TRAF1 (H-132) - sc-1831 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
TRAF1 (H-132): sc-1831. Immunoperoxidase staining of formalin fixed, paraffin-embedded human lymph node tissue showing cytoplasmic and membane  staining of cells in germinal centers and cells in non-germinal centers.

TRAF1 (H-186) - sc-7186 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
TRAF1 (H-186): sc-7186. Western blot analysis of TRAF1 expression in TRAF1 transfected NIH/3T3 cells.

TRAF1 (H-3) - sc-6253 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TRAF1 (H-3): sc-6253. Western blot analysis of TRAF1 expression in IB4 cells transfected with a TRAF1 expression vector (A) and non-transfected control (B).

Anti-TRAF1 antibody - ab129279 from Abcam

Prices $407.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-TRAF1 antibody (ab129279) at 0.5 µg/ml (for 1 hour) + U937 cell lysate (in RIPA buffer) at 35 µgdeveloped using the ECL technique

Anti-TRAF1 antibody - ab197684 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-TRAF1 antibody (ab197684) at 1/350 dilution + Human lymphoma tissue lysate at 40 µg

Anti-TRAF1 antibody - ab167652 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-TRAF1 antibody (ab167652) at 1 µg/mlLane 1 : TRAF1 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG HRP at 1/2500 dilution

Anti-TRAF1 antibody - ab116313 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-TRAF1 antibody (ab116313) at 1/100 dilution + NCI-H460 cell line lysates at 35 µg

Anti-TRAF1 antibody - ab48002 from Abcam

Prices $370.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-TRAF1 antibody (ab48002) at 0.5 µg/ml + U937 cell lysate (RIPA buffer) at 35 µgdeveloped using the ECL technique

Anti-TRAF1 antibody - ab155268 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-TRAF1 antibody (ab155268) at 1/3000 dilution + Raji whole cell lysate at 30 µg

Anti-TRAF1 antibody - ab37410 from Abcam

Prices $359.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-TRAF1 Antibody (aa270-282) IHC-plus™ - LS-B6466 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-TRAF1 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6466 concentration 2.5 ug/ml.

Anti-TRAF1 Antibody (aa55-83, FITC) - LS-C224420 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TRAF1 Antibody (aa55-83, Biotin) - LS-C224419 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TRAF1 Antibody (aa55-83, APC) - LS-C224418 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TRAF1 Antibody (aa55-83, Azide-free, HRP) - LS-C224421 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TRAF1 Antibody (aa55-83, AP) - LS-C224417 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TRAF1 Antibody (aa55-83, PE) - LS-C224422 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TRAF1 Antibody (aa54-83) - LS-C325904 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TRAF1 Antibody (clone 3D4) - LS-C343625 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3D4

Anti-TRAF1 Antibody (C-Terminus) - LS-C112308 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
TRAF1 antibody LS-C112308 Western blot of 293T Cell lysate. Antibody concentration 1 ug/ml.
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