TRAF1

Gene Symbol TRAF1
Entrez Gene 7185
Alt Symbol EBI6, MGC:10353
Species Human
Gene Type protein-coding
Description TNF receptor-associated factor 1
Other Description Epstein-Bar virus-induced protein 6
Swissprots Q8NF13 Q13077 B4DJ77 Q658U1
Accessions CBX47545 EAW87479 Q13077 AK090468 BAC03449 AK295959 BAG58739 AK315476 BAG37860 AL832989 CAH56343 AW014547 BC024145 AAH24145 BT019408 AAV38215 HQ447750 ADQ32235 U19261 AAA62309 NM_001190945 NP_001177874 NM_001190947 NP_001177876 NM_005658 NP_005649
Function Adapter molecule that regulates the activation of NF- kappa-B and JNK. Plays a role in the regulation of cell survival and apoptosis. The heterotrimer formed by TRAF1 and TRAF2 is part of a E3 ubiquitin-protein ligase complex that promotes ubiquitination of target proteins, such as MAP3K14. The TRAF1/TRAF2 complex recruits the antiapoptotic E3 protein- ubiquitin ligases BIRC2 and BIRC3 to TNFRSF1B/TNFR2. {ECO:0000269|PubMed:10692572, ECO:0000269|PubMed:16323247, ECO:0000269|PubMed:18429822, ECO:0000269|PubMed:19287455, ECO:0000269|PubMed:19698991, ECO:0000269|PubMed:20385093}.
Top Pathways Small cell lung cancer, Herpes simplex infection, Viral carcinogenesis, Epstein-Barr virus infection, TNF signaling pathway

TRAF1 - MBS1276403 from MyBioSource

Species Human
Accession BC024145

Human TRAF1 ORF Clone(NM_001190947.1) - CDCR358105 from Creative Biomart

Species Human
Accession NM_001190947.1

Human TRAF1 ORF Clone(NM_001190947.1) - CDCR358107 from Creative Biomart

Species Human
Accession NM_001190947.1

Human TRAF1 ORF Clone(NM_005658.4) - CDCL179483 from Creative Biomart

Species Human
Accession NM_005658.4

human TRAF1 ORF clone - CDCH094472 from Creative Biomart

Species Human
Accession NM_001190945

human TRAF1 ORF clone - CDCH094473 from Creative Biomart

Species Human
Accession NM_001190945

human TRAF1 ORF clone - CDCH094474 from Creative Biomart

Species Human
Accession NM_001190945

human TRAF1 ORF clone - CDCH094475 from Creative Biomart

Species Human
Accession NM_001190945

Human TRAF1 Gene cDNA clone plasmid - HG11301-M from Sino Biological

Species Human

Human TRAF1 natural ORF mammalian expression plasmid, N-OFPSpark tag - HG11301-ANR from Sino Biological

Species Human
Accession NM_005658.3

human TRAF1 ORF clone (NM_001190947.1) - CDCH094474 from Creative biogene

Species Human

Human TRAF1 ORF Clone (BC024145) - CDCS409224 from Creative biogene

Species Human
Accession Q13077
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