MYC

Gene Symbol MYC
Entrez Gene 4609
Alt Symbol MRTL, MYCC, bHLHe39, c-Myc
Species Human
Gene Type protein-coding
Description v-myc avian myelocytomatosis viral oncogene homolog
Other Description avian myelocytomatosis viral oncogene homolog|class E basic helix-loop-helix protein 39|myc proto-oncogene protein|myc-related translation/localization regulatory factor|proto-oncogene c-Myc|transcription factor p64|v-myc myelocytomatosis viral oncogene homolog
Swissprots Q14026 P01107 A8WFE7 P01106
Accessions AAA59880 AAA59881 AAA59882 AAA59884 AAA59886 AAA59887 AAA88090 AAO21131 AAO31951 ABW69847 BAA01374 BAA01375 CAA25015 CAA25095 CAA25105 CAA25106 CAA25288 CAC22425 CAL18306 CAL18307 CAL18308 CAL18309 CAL18310 CAL18311 CAL18312 CAL18313 CAL18314 CAL18315 CAL18316 CAL18317 CAL18318 CAL18319 CAL18320 CAL18321 CAL18322 CAL18323 CAL18324 CAL18325 CAL18326 CAL18327 CAL18328 CAL18329 CAL18330 CAL18331 CAL18332 CAL18333 CAL18334 CAL18335 CAL18336 CAL18337 CAL18338 CAL18340 CAL18341 CAL18342 CAL18343 CAL18344 CAL18345 CAL18346 CAL18347 CAL18348 CAL18349 CAL18350 CAL18351 CAL18352 CAL18353 CAL18354 CAL18355 CAL18356 CAL18357 CAL18358 CAL18359 CAL18360 CAL18361 CAL18362 CAL18363 CAL18364 CAL18365 CAL18366 CAL18367 CAL18368 CAL18369 CAL18370 CAL18371 CAL18372 CAL18373 CAL18374 CAL18375 CAL18376 CAL18377 CAL18378 CAL18379 CAL18380 CAL18619 CAL18620 CAL18621 CAL18622 CAL18623 CAL18624 CAM91152 CAN37626 CBI12209 CBX47660 CBX54352 CCW44111 CDI30193 EAW92098 EAW92099 EAW92100 EAW92101 P01106 AA807892 AK303921 BAG64849 AK312883 BAG35731 BC000141 AAH00141 BC000917 AAH00917 BC058901 AAH58901 BG499628 BK006467 DAA06340 BT019768 AAV38573 DQ894085 ABM85011 K02276 AAA36340 KC782559 AGV06354 M13929 AAA88091 M13930 AAA88093 V00568 CAA23831 X66258 CAA46984 NM_002467 NP_002458
Function Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'- CAC[GA]TG-3'. Activates the transcription of growth-related genes.
Subcellular Location Nucleus, nucleoplasm {ECO:0000269|PubMed:17558397}. Nucleus, nucleolus {ECO:0000269|PubMed:17558397}.
Top Pathways MicroRNAs in cancer, Wnt signaling pathway, Central carbon metabolism in cancer, Signaling pathways regulating pluripotency of stem cells, Hippo signaling pathway

c-Myc (D84C12) Rabbit mAb (Pacific Blue™ Conjugate) - 14426 from Cell Signaling Technology

Prices $299.00
Sizes 100 µl (50 tests)
Host Rabbit
Clonality Monoclonal
Clone D84C12
Flow cytometric analysis of Jurkat cells using c-Myc (D84C12) Rabbit mAb (Pacific Blue™ Conjugate) (green) compared to Rabbit (DA1E) mAb IgG XP ® Isotype Control (Pacific Blue™ Conjugate) #9078 (red).

c-Myc (D84C12) Rabbit mAb (PE Conjugate) - 14819 from Cell Signaling Technology

Prices $299.00
Sizes 100 µl (50 tests)
Host Rabbit
Clonality Monoclonal
Clone D84C12
Flow cytometric analysis of Jurkat cells using c-Myc (D84C12) Rabbit mAb (PE Conjugate) (green) compared to Rabbit (DA1E) mAb IgG XP ® Isotype Control (PE Conjugate) #5742 (red).

c-Myc (D84C12) Rabbit mAb (Alexa Fluor ® 488 Conjugate) - 12855 from Cell Signaling Technology

Prices $299.00
Sizes 100 µl (50 tests)
Host Rabbit
Clonality Monoclonal
Clone D84C12
Flow cytometric analysis of Jurkat cells using c-Myc (D84C12) Rabbit mAb (Alexa Fluor ® 488 Conjugate) (green) compared to concentration matched Rabbit (DA1E) mAb IgG XP ® Isotype Control (Alexa Fluor ® 488 Conjugate) #2975 (red).

c-Myc (D84C12) Rabbit mAb (Alexa Fluor ® 647 Conjugate) - 13871 from Cell Signaling Technology

Prices $299.00
Sizes 100 µl (50 tests)
Host Rabbit
Clonality Monoclonal
Clone D84C12
Flow cytometric analysis of Jurkat cells using c-Myc (D84C12) Rabbit mAb (Alexa Fluor ® 647 Conjugate) (green) compared to Rabbit (DA1E) mAb IgG XP ® Isotype Control (Alexa Fluor ® 647 Conjugate) #2985 (red).

c-Myc (D84C12) XP ® Rabbit mAb (PE Conjugate) - 12189 from Cell Signaling Technology

Host Rabbit
Clonality Monoclonal
Clone D84C12

Phospho-c-Myc (Ser62) (E1J4K) Rabbit mAb - 13748 from Cell Signaling Technology

Prices $287.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone E1J4K
Western blot analysis of extracts from KARPAS-299, cells untreated (-) or treated with MG-132 #2194 (10 μM, overnight; +) using Phospho-c-Myc (Ser62) (E1J4K) Rabbit mAb. The phospho-specificity of the antibody was demonstrated by peptide competition using phosphopeptides containing Ser62, Thr58/Ser62, Thr58, or a nonphosphorylated peptide as indicated.

c-Myc Antibody - 9402 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from HeLa cells 48 hours following mock transfection, transfection with nonspecific (control) siRNA or transfection with c-Myc siRNA. c-Myc was detected using c-Myc Antibody #9402, and p42 was detected using p42 MAPK Antibody #9108. The c-Myc Antibody confirms silencing of c-Myc expression, and the p42 MAPK Antibody is used to control for protein loading and siRNA specificity.

c-Myc (D84C12) Rabbit mAb - 5605 from Cell Signaling Technology

Prices $99.00, $246.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D84C12
Western blot analysis of extracts from HeLa cells, mock transfected or transfected with SignalSilence ® c-Myc siRNA I #6341, using c-Myc (D84C12) Rabbit mAb.

c-Myc (D3N8F) Rabbit mAb - 13987 from Cell Signaling Technology

Prices $99.00, $246.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D3N8F
Western blot analysis of extracts from various cell lines using c-Myc (D3N8F) Rabbit mAb.

Phospho-c-Myc (Thr58/Ser62) Antibody - 9401 from Cell Signaling Technology

Host Rabbit
Clonality Polyclonal

p-c-Myc (Thr 58) - sc-135647 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
p-c-Myc (Thr 58): sc-135647. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human breast carcinoma tissue showing nuclear localization.

p-c-Myc (Ser 373) - sc-101739 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
p-c-Myc (Ser 373): sc-101739. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human breast carcinoma tissue showing nuclear staining.

p-c-Myc (Thr 358) - sc-101740 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
p-c-Myc (Thr 358): sc-101740. Western blot analysis of phosphorylated c-Myc expression in untreated (A) and UV-treated (B) HT-29 whole cell lysates.

c-Myc (9E10) - sc-40 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Western blot analysis of c-Myc expression in HeLa (A,D,F), Jurkat (B), K-562 (C) and NIH/3T3 (G) whole cell lysates and Jurkat (E,H) nuclear extracts. Antibodies tested include c-Myc (9E10): sc-40 (A-C), c-Myc (C-33): sc-42 (D,E) and c-Myc (N-262): sc-764 (F-H).

c-Myc (G-4) - sc-373712 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
c-Myc (G-4): sc-373712. Western blot analysis of c-Myc expression in non-transfected: sc-117752 (A) and mouse c-Myc transfected: sc-118892 (B) 293T whole cell lysates.

c-Myc (A-14) - sc-789 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
c-Myc (A-14) PE: sc-789 PE. Intracellular FCM analysis of methanol permeabilized HeLa cells. Solid black line histogram represents control goat IgG.

c-Myc (C-12) - sc-398624 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
c-Myc (C-12): sc-398624. Western blot analysis of c-Myc expression in non-transfected: sc-117752 (A) and mouse c-Myc transfected: sc-118892 (B) 293T whole cell lysates.

c-Myc (C-19) - sc-788 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
c-Myc (C-19): sc-788. Immunoperoxidase staining of formalin-fixed, paraffin-embedded mouse uterus tissue showing nuclear localization.

c-Myc (C-33) - sc-42 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Western blot analysis of c-Myc expression in HeLa (A,D,F), Jurkat (B), K-562 (C) and NIH/3T3 (G) whole cell lysates and Jurkat (E,H) nuclear extracts. Antibodies tested include c-Myc (9E10): sc-40 (A-C), c-Myc (C-33): sc-42 (D,E) and c-Myc (N-262): sc-764 (F-H).

c-Myc (9E11) - sc-47694 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
c-Myc (9E11): sc-47694. Western blot analysis of c-Myc expression in non-transfected COS (A) and c-Myc fusion protein transfected COS (B) whole cell lysates.

c-Myc (C-8) - sc-41 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
c-Myc (C-8): sc-41. Western blot analysis of c-Myc of 5 ng of c-Myc (1-262): sc-4084 WB.

c-Myc (N-262) - sc-764 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Western blot analysis of human recombinant c-Myc fusion protein untreated (A,C) or phosphorylated by p38α (B,D). Antibodies tested include c-Myc (N-262): sc-764 (A,B) and p-c-Myc (Thr 58/Ser 62)-R: sc-8000-R (C,D).

c-Myc (6A10) - sc-53854 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal
c-Myc (6A10): sc-53854. Western blot analysis of c-Myc expression in nontransfected Cos (A) and c-Myc-transfected Cos (B) whole cell lysates.

c-Myc (SPM237) - sc-56505 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
c-Myc (SPM237): sc-56505. Western blot analysis of c-Myc expression in HeLa whole cell lysate.

c-Myc (Myc.A7) - sc-56634 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
c-Myc (Myc.A7): sc-56634. Western blot analysis of c-Myc expression in nontransfected Cos (A) and c-Myc-transfected Cos (B) whole cell lysates.
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