Gene Symbol | TBXA2R |
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Entrez Gene | 6915 |
Alt Symbol | BDPLT13, TXA2-R |
Species | Human |
Gene Type | protein-coding |
Description | thromboxane A2 receptor |
Other Description | prostanoid TP receptor |
Swissprots | P21731 Q9UCY1 Q6DK52 Q9UCY2 O75228 |
Accessions | AAC24302 AAC24303 ABB72549 BAA03649 EAW69301 EAW69302 P21731 AY429110 AAR07905 BC028027 AAH28027 BC074749 AAH74749 BC074750 AAH74750 BC121148 AAI21149 BC121149 AAI21150 BM990145 U11271 AAA58957 U27325 AAA68608 XM_011528214 XP_011526516 NM_001060 NP_001051 NM_201636 NP_963998 |
Function | Receptor for thromboxane A2 (TXA2), a potent stimulator of platelet aggregation. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. In the kidney, the binding of TXA2 to glomerular TP receptors causes intense vasoconstriction. Activates phospholipase C. Isoform 1 activates adenylyl cyclase. Isoform 2 inhibits adenylyl cyclase. {ECO:0000269|PubMed:8613548}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Top Pathways | Calcium signaling pathway, Neuroactive ligand-receptor interaction |
TXA2R (H-120) - sc-30036 from Santa Cruz Biotechnology
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TXA2R (P-20) - sc-31260 from Santa Cruz Biotechnology
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TXA2R (T-20) - sc-18377 from Santa Cruz Biotechnology
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TXA2R (A-14) - sc-31261 from Santa Cruz Biotechnology
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TXA2R (L-16) - sc-31262 from Santa Cruz Biotechnology
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Anti-Thromboxane A2 receptor antibody - ab85544 from Abcam
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Anti-Thromboxane A2 receptor antibody [EPR7336] - ab134959 from Abcam
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Anti-Thromboxane A2 receptor antibody - N-terminal - ab137607 from Abcam
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Anti-Thromboxane A2 Receptor Antibody (FITC) - LS-C146699 from LifeSpan Bioscience
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Anti-Thromboxane A2 Receptor Antibody - LS-C150701 from LifeSpan Bioscience
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Anti-Thromboxane A2 Receptor Antibody - LS-C146680 from LifeSpan Bioscience
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Anti-Thromboxane A2 Receptor Antibody - LS-C137417 from LifeSpan Bioscience
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Anti-Thromboxane A2 Receptor Antibody (aa37-86) - LS-C151799 from LifeSpan Bioscience
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Anti-Thromboxane A2 Receptor Antibody (Internal, clone EPR7336) - LS-C154733 from LifeSpan Bioscience
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Anti-Thromboxane A2 Receptor Antibody (Cytoplasmic Domain) IHC-plus™ - LS-A1278 from LifeSpan Bioscience
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Anti-Thromboxane A2 Receptor Antibody (Cytoplasmic Domain) IHC-plus™ - LS-A1277 from LifeSpan Bioscience
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Anti-Thromboxane A2 Receptor Antibody (aa323-343) IHC-plus™ - LS-B2465 from LifeSpan Bioscience
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Anti-Thromboxane A2 Receptor Antibody (C-Terminus) IHC-plus™ - LS-A1280 from LifeSpan Bioscience
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Anti-Thromboxane A2 Receptor Antibody IHC-plus™ - LS-B4842 from LifeSpan Bioscience
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Thromboxane A2 R/TBXA2R Antibody - NBP1-40198 from Novus Biologicals
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Thromboxane A2 R/TBXA2R Antibody - NBP1-31106 from Novus Biologicals
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Thromboxane A2 R/TBXA2R Antibody - NLS1277 from Novus Biologicals
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Thromboxane A2 R/TBXA2R Antibody - NLS1280 from Novus Biologicals
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Thromboxane A2 R/TBXA2R Antibody - NLS1278 from Novus Biologicals
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Anti-TBXA2R (N-terminal) antibody produced in rabbit - SAB2700057 from Sigma-Aldrich
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