Gene Symbol | TBXA2R |
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Entrez Gene | 6915 |
Alt Symbol | BDPLT13, TXA2-R |
Species | Human |
Gene Type | protein-coding |
Description | thromboxane A2 receptor |
Other Description | prostanoid TP receptor |
Swissprots | P21731 Q9UCY1 Q6DK52 Q9UCY2 O75228 |
Accessions | AAC24302 AAC24303 ABB72549 BAA03649 EAW69301 EAW69302 P21731 AY429110 AAR07905 BC028027 AAH28027 BC074749 AAH74749 BC074750 AAH74750 BC121148 AAI21149 BC121149 AAI21150 BM990145 U11271 AAA58957 U27325 AAA68608 XM_011528214 XP_011526516 NM_001060 NP_001051 NM_201636 NP_963998 |
Function | Receptor for thromboxane A2 (TXA2), a potent stimulator of platelet aggregation. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. In the kidney, the binding of TXA2 to glomerular TP receptors causes intense vasoconstriction. Activates phospholipase C. Isoform 1 activates adenylyl cyclase. Isoform 2 inhibits adenylyl cyclase. {ECO:0000269|PubMed:8613548}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Top Pathways | Calcium signaling pathway, Neuroactive ligand-receptor interaction |
Thromboxane A2 Receptor Antibody Blocking Peptide - LS-E23597 from LifeSpan Bioscience
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Thromboxane A2 Receptor Antibody Blocking Peptide - LS-E28212 from LifeSpan Bioscience
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Thromboxane A2 Receptor Antibody Blocking Peptide - LS-E28211 from LifeSpan Bioscience
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Thromboxane A2 Receptor Antibody Blocking Peptide - LS-E28213 from LifeSpan Bioscience
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TBXA2R-Antibody-Center-Blocking-Peptide - BP9264c from Abgent, a WuXi AppTec company
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Recombinant Thromboxane Receptor (TP) - RPC822Hu01 from Uscn Life Science Inc.
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ChemiScreen™ Membrane Preparation Recombinant Human TBXA2R (TP) Thromboxane Receptor - HTS081M from EMD Millipore
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Recombinant Thromboxane Receptor (TP) - RPC822Hu01 from Cloud-clone
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TBXA2R Protein - abx163330 from Abbexa
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Thromboxane A2 receptor (TBXA2R), Recombinant Protein - MBS1085758 from MyBioSource
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TBXA2R Peptide, Human - M34GP15692H from Creative Peptides
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TBXA2R Recombinant Protein (OPCD00766) - OPCD00766 from Aviva Systems Biology
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Thromboxane A2 R/TBXA2R Recombinant Protein Antigen - NBP2-57802PEP from Novus Biologicals
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