Gene Symbol | TBXA2R |
---|---|
Entrez Gene | 6915 |
Alt Symbol | BDPLT13, TXA2-R |
Species | Human |
Gene Type | protein-coding |
Description | thromboxane A2 receptor |
Other Description | prostanoid TP receptor |
Swissprots | P21731 Q9UCY1 Q6DK52 Q9UCY2 O75228 |
Accessions | AAC24302 AAC24303 ABB72549 BAA03649 EAW69301 EAW69302 P21731 AY429110 AAR07905 BC028027 AAH28027 BC074749 AAH74749 BC074750 AAH74750 BC121148 AAI21149 BC121149 AAI21150 BM990145 U11271 AAA58957 U27325 AAA68608 XM_011528214 XP_011526516 NM_001060 NP_001051 NM_201636 NP_963998 |
Function | Receptor for thromboxane A2 (TXA2), a potent stimulator of platelet aggregation. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. In the kidney, the binding of TXA2 to glomerular TP receptors causes intense vasoconstriction. Activates phospholipase C. Isoform 1 activates adenylyl cyclase. Isoform 2 inhibits adenylyl cyclase. {ECO:0000269|PubMed:8613548}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Top Pathways | Calcium signaling pathway, Neuroactive ligand-receptor interaction |
Human Thromboxane A2 R/TBXA2R (NP_001051) VersaClone cDNA - RDC0185 from R&D Systems
|
||||||
Human TBXA2R cDNA clone(NM_201636.2) - CDFG013384 from Creative Biomart
|
||||||
human TBXA2R ORF clone - CDCH089528 from Creative Biomart
|
||||||
human TBXA2R ORF clone - CDCH089529 from Creative Biomart
|
||||||
human TBXA2R ORF clone - CDCH089530 from Creative Biomart
|
||||||
human TBXA2R ORF clone - CDCH089531 from Creative Biomart
|
||||||
Human TBXA2R ORF Clone(NM_001060.5) - CDCL178026 from Creative Biomart
|
||||||
Human TBXA2R ORF Clone(NM_201636.2) - CDCR327118 from Creative Biomart
|
||||||
Human TBXA2R ORF Clone(NM_201636.2) - CDCR327119 from Creative Biomart
|
||||||
Human TBXA2R ORF Clone(NM_201636.2) - CDCR327120 from Creative Biomart
|
||||||
Human TBXA2R ORF Clone(NM_201636.2) - CDCR327121 from Creative Biomart
|
||||||
human TBXA2R ORF clone (NM_201636.2) - CDCH089530 from Creative biogene
|
||||||
Human TBXA2R cDNA Clone(NM_201636.2) - CDFG013384 from Creative biogene
|
||||||