NEK7

Gene Symbol NEK7
Entrez Gene 140609
Alt Symbol -
Species Human
Gene Type protein-coding
Description NIMA-related kinase 7
Other Description NIMA (never in mitosis gene a)-related kinase 7|never in mitosis A-related kinase 7|nimA-related protein kinase 7|serine/threonine-protein kinase Nek7
Swissprots Q8TDX7 A6NGT8
Accessions EAW91293 EAW91294 EAW91295 EAW91296 Q8TDX7 AB062450 BAB85632 AK313411 BAG36205 AL080111 BC043003 BC152872 AAI52873 BC156616 AAI56617 DB498485 XM_011509208 XP_011507510 XM_011509209 XP_011507511 NM_133494 NP_598001
Function Protein kinase which plays an important role in mitotic cell cycle progression. Required for microtubule nucleation activity of the centrosome, robust mitotic spindle formation and cytokinesis. Phosphorylates RPS6KB1. {ECO:0000269|PubMed:17101132, ECO:0000269|PubMed:17586473, ECO:0000269|PubMed:19414596}.
Subcellular Location Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Present at centrosome throughout the cell cycle. Also detected at spindle midzone of the anaphase cells and eventually concentrates at the midbody.
Tissue Specificity Highly expressed in lung, muscle, testis, brain, heart, liver, leukocyte and spleen. Lower expression in ovary, prostate and kidney. No expression seen in small intestine. {ECO:0000269|PubMed:11701951}.

NEK7 (C34C3) Rabbit mAb - 3057 from Cell Signaling Technology

Prices $99.00, $246.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone C34C3
Western blot analysis of GST-NEK6 and GST-NEK7 fusion proteins and extracts from HeLa and Jurkat cells using NEK7 (C34C3) Rabbit mAb.

Nek7 (B-5) - sc-393539 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Nek7 (B-5): sc-393539. Western blot analysis of Nek7 expression in non-transfected 293T: sc-117752 (A), mouse Nek7 transfected 293T: sc-122001 (B), HeLa (C), Jurkat (D) and NIH/3T3 (E) whole cell lysates.

Nek7 (A-12) - sc-398439 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Nek7 (A-12): sc-398439. Western blot analysis of Nek7 expression in non-transfected 293T: sc-117752 (A), mouse Nek7 transfected 293T: sc-122001 (B), HeLa (C), Jurkat (D) and NIH/3T3 (E) whole cell lysates.

Nek7 (C-15) - sc-50755 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Nek7 (C-15): sc-50755. Western blot analysis of Nek7 expression in non-transfected: sc-117752 (A) and mouse Nek7 transfected: sc-122001 (B) 293T whole cell lysates.

Nek7 (N-20) - sc-50756 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Nek7 (N-20): sc-50756. Western blot analysis of Nek7 expression in non-transfected: sc-117752 (A) and mouse Nek7 transfected: sc-122001 (B) 293T whole cell lysates.

Nek7 (P-16) - sc-50757 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-NEK7 antibody - ab96538 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-NEK7 antibody (ab96538) at 1/500 dilution + HeLa S3 whole cell lysate at 30 µg

Anti-NEK7 antibody - ab101608 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab101608 at 5 µg/ml staining NEK7 in Human cerebellum by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue.

Anti-NEK7 antibody - ab68060 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-NEK7 antibody (ab68060) at 1/500 dilutionLane 1 : NEK7 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-NEK7 antibody [EPR4900] - ab133514 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4900
All lanes : Anti-NEK7 antibody [EPR4900] (ab133514) at 1/10000 dilutionLane 1 : Jurkat cell lysateLane 2 : A549 cell lysateLane 3 : C6 cell lysateLane 4 : RAW264.7 cell lysateLane 5 : PC12 cell lysateLane 6 : NIH/3T3 cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat-anti-rabbit HRP at 1/2000 dilutiondeveloped using the ECL technique

Anti-NEK7 antibody [EPR4901] - ab109433 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4901
All lanes : Anti-NEK7 antibody [EPR4901] (ab109433) at 1/10000 dilutionLane 1 : Human brain lysateLane 2 : HeLa cell lysateLane 3 : A549 cell lysateLane 4 : HepG2 cell lysateLane 5 : Fetal liver lysateLane 6 : Jurkat cell lysateLysates/proteins at 10 µg per lane.

Anti-NEK7 Antibody (C-Terminus) - LS-C146138 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
NEK7 antibody LS-C146138 Western blot of Rat Liver lysate. Antibody concentration 1 ug/ml.

Anti-NEK7 Antibody (Internal, clone EPR4900) - LS-C138687 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4900
Western blot analysis on (A) Jurkat, (B) A549, (C) C6, (D) RAW264.7, (E) PC-12, and (F) NIH/3T3 cell lysates using anti-NEK7 antibody.

Anti-NEK7 Antibody (aa74-123) - LS-C81339 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
HepG2 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-NEK7 Antibody (N-Terminus, AP) - LS-C220148 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NEK7 Antibody (aa274-286) - LS-C139711 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
NEK7 antibody (0.1 ug/ml) staining of Human Lung lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-NEK7 Antibody (N-Terminus, APC) - LS-C220149 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NEK7 Antibody (Internal, clone EPR4901) - LS-C138558 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4901
Western blot analysis on (A) human brain, (B) HeLa, (C) A549, (D) HepG2, (E) fetal liver, and (F) Jurkat lysates using anti-NEK7 antibody.

Anti-NEK7 Antibody (N-Terminus, Biotin) - LS-C220150 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NEK7 Antibody (N-Terminus, FITC) - LS-C220151 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NEK7 Antibody (N-Terminus, Azide-free, HRP) - LS-C220152 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NEK7 Antibody (N-Terminus, PE) - LS-C220153 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NEK7 Antibody (aa101-150) - LS-C199305 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human lung carcinoma tissue, using NEK7 Antibody. The sample on the right was incubated with synthetic peptide.

Anti-NEK7 Antibody (aa1-50) - LS-C286944 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human NEK7 by Immunohistochemistry. Sample: FFPE section of human non-small cell lung cancer. Antibody: Affinity purified rabbit anti-NEK7 used at a dilution of 1:250.

Anti-NEK7 Antibody (aa238-302) - LS-C185958 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded Tw2.6 xenograft using NEK7 antibody at 1:100 dilution.
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