NEK7

Gene Symbol	NEK7
Entrez Gene	140609
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	NIMA-related kinase 7
Other Description	NIMA (never in mitosis gene a)-related kinase 7|never in mitosis A-related kinase 7|nimA-related protein kinase 7|serine/threonine-protein kinase Nek7
Swissprots	Q8TDX7 A6NGT8
Accessions	EAW91293 EAW91294 EAW91295 EAW91296 Q8TDX7 AB062450 BAB85632 AK313411 BAG36205 AL080111 BC043003 BC152872 AAI52873 BC156616 AAI56617 DB498485 XM_011509208 XP_011507510 XM_011509209 XP_011507511 NM_133494 NP_598001
Function	Protein kinase which plays an important role in mitotic cell cycle progression. Required for microtubule nucleation activity of the centrosome, robust mitotic spindle formation and cytokinesis. Phosphorylates RPS6KB1. {ECO:0000269|PubMed:17101132, ECO:0000269|PubMed:17586473, ECO:0000269|PubMed:19414596}.
Subcellular Location	Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Present at centrosome throughout the cell cycle. Also detected at spindle midzone of the anaphase cells and eventually concentrates at the midbody.
Tissue Specificity	Highly expressed in lung, muscle, testis, brain, heart, liver, leukocyte and spleen. Lower expression in ovary, prostate and kidney. No expression seen in small intestine. {ECO:0000269|PubMed:11701951}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NEK7 ORF clone(NM_133494.2) - CDCL185457 from Creative Biomart Species Human Accession NM_133494.2

Human NEK7 ORF clone(NM_133494.2) - CDCH391654 from Creative Biomart Species Human Accession NM_133494.2

Human NEK7 Gene ORF cDNA clone in cloning vector - HG11534-M from Sino Biological Species Human

Human NEK7 Gene ORF cDNA clone expression plasmid, N-HA tag - HG11534-NY from Sino Biological Species Human

Human NEK7 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG11534-ACG from Sino Biological Species Human

Human NEK7 Gene ORF cDNA clone expression plasmid, C-HA tag - HG11534-CY from Sino Biological Species Human

Human NEK7 Gene ORF cDNA clone expression plasmid, N-His tag - HG11534-NH from Sino Biological Species Human

Human NEK7 Gene ORF cDNA clone expression plasmid, C-His tag - HG11534-CH from Sino Biological Species Human

Human NEK7 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG11534-NF from Sino Biological Species Human

Human NEK7 Gene cDNA Clone (full-length ORF Clone), expression ready, untagged - HG11534-M-N from Sino Biological Species Human Accession NM_133494.2

Human NEK7 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG11534-CF from Sino Biological Species Human

Human NEK7 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG11534-NM from Sino Biological Species Human

Human NEK7 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG11534-CM from Sino Biological Species Human

Human NEK7 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG11534-ACR from Sino Biological Species Human

Human NEK7 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG11534-ANR from Sino Biological Species Human

Human NEK7 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG11534-ANG from Sino Biological Species Human

Human NEK7 Gene ORF cDNA clone expression plasmid - HG11534-UT from Sino Biological Species Human

Human NEK7 ORF clone(NM_133494.2) - CDCL185457 from Creative biogene Species Human

Search more