NEK7

Gene Symbol NEK7
Entrez Gene 140609
Alt Symbol -
Species Human
Gene Type protein-coding
Description NIMA-related kinase 7
Other Description NIMA (never in mitosis gene a)-related kinase 7|never in mitosis A-related kinase 7|nimA-related protein kinase 7|serine/threonine-protein kinase Nek7
Swissprots Q8TDX7 A6NGT8
Accessions EAW91293 EAW91294 EAW91295 EAW91296 Q8TDX7 AB062450 BAB85632 AK313411 BAG36205 AL080111 BC043003 BC152872 AAI52873 BC156616 AAI56617 DB498485 XM_011509208 XP_011507510 XM_011509209 XP_011507511 NM_133494 NP_598001
Function Protein kinase which plays an important role in mitotic cell cycle progression. Required for microtubule nucleation activity of the centrosome, robust mitotic spindle formation and cytokinesis. Phosphorylates RPS6KB1. {ECO:0000269|PubMed:17101132, ECO:0000269|PubMed:17586473, ECO:0000269|PubMed:19414596}.
Subcellular Location Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Present at centrosome throughout the cell cycle. Also detected at spindle midzone of the anaphase cells and eventually concentrates at the midbody.
Tissue Specificity Highly expressed in lung, muscle, testis, brain, heart, liver, leukocyte and spleen. Lower expression in ovary, prostate and kidney. No expression seen in small intestine. {ECO:0000269|PubMed:11701951}.

Nek7 CRISPR/Cas9 KO Plasmid (h) - sc-405218 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nek7 HDR Plasmid (h) - sc-405218-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nek7 Double Nickase Plasmid (h) - sc-405218-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nek7 Double Nickase Plasmid (h2) - sc-405218-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nek7 CRISPR Activation Plasmid (h) - sc-405218-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nek7 CRISPR Activation Plasmid (h2) - sc-405218-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nek7 Lentiviral Activation Particles (h) - sc-405218-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nek7 Lentiviral Activation Particles (h2) - sc-405218-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nek7 siRNA (h) - sc-61174 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Nek7 shRNA Plasmid (h) - sc-61174-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Nek7 shRNA (h) Lentiviral Particles - sc-61174-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU050581 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

MISSION® siRNA - SIHK1409 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK1408 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK1410 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN15204 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15204 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

NEK7 siRNA (Human) - CRJ5291 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NEK7 RNAi - H00140609-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human Nek7 (NM_133494.2) - SHH351284 from Creative biogene

Category siRNA
Species Reactivities Human

NEK7 shRNA Plasmid (Human) - CHJ5291 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NEK7 miRNA 3'UTR clone - MiUTR4H-TG11831 from Creative biogene

Species Reactivities Human
Search more