NLGN1

Gene Symbol	NLGN1
Entrez Gene	22871
Alt Symbol	NL1
Species	Human
Gene Type	protein-coding
Description	neuroligin 1
Other Description	neuroligin-1
Swissprots	Q9UPT2 Q8N2Q7
Accessions	EAW78453 EAW78454 EAW78455 EAW78456 Q8N2Q7 AB028993 BAA83022 AF086015 AK074522 BAC11039 AK129874 AK307813 BC032555 AAH32555 CB052838 DA310134 DQ891239 ABM82165 EU176566 ABW03367 GQ489206 ADB12633 XM_005247232 XP_005247289 XM_005247233 XP_005247290 XM_005247234 XP_005247291 XM_005247235 XP_005247292 XM_005247236 XP_005247293 XM_005247237 XP_005247294 XM_006713540 XP_006713603 XM_011512551 XP_011510853 XM_011512552 XP_011510854 XM_011512553 XP_011510855 XM_011512554 XP_011510856 XM_011512555 XP_011510857 NM_014932 NP_055747
Function	Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses. Required to maintain wakefulness quality and normal synchrony of cerebral cortex activity during wakefulness and sleep. {ECO:0000250|UniProtKB:Q99K10}.
Subcellular Location	Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cell junction, synapse {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000250}. Note=Enriched in synaptic plasma membranes and clustered in synaptic clefts and postsynaptic densities. Detected at dendritic spines. Colocalized with DLG4/PSD-95 and GRIN1/NMDAR1 (By similarity). {ECO:0000250}.
Tissue Specificity	Expressed in the blood vessel walls (at protein level). Detected in brain, and at lower levels in pancreas islet beta cells. {ECO:0000269|PubMed:18755801, ECO:0000269|PubMed:19926856}.
Top Pathways	Cell adhesion molecules (CAMs)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NLGN1 gene - orb92734 from Biorbyt Prices $366.00 Sizes 10 μg Species Human

NLGN1 - MBS1269218 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC032555

Human NLGN1 cDNA clone(NM_014932.2) - CDFH012587 from Creative Biomart Species Human Accession NM_014932.2

Human NLGN1 cDNA clone(NM_014932.2) - CDFH012588 from Creative Biomart Species Human Accession NM_014932.2

Human NLGN1 ORF Clone(NM_014932.2) - CDCR298578 from Creative Biomart Species Human Accession NM_014932.2

Human NLGN1 ORF Clone(NM_014932.2) - CDCR298579 from Creative Biomart Species Human Accession NM_014932.2

Human NLGN1 ORF clone(NM_014932.2) - CDCL185489 from Creative Biomart Species Human Accession NM_014932.2

Human Neuroligin 1/NLGN1 Gene ORF cDNA clone in cloning vector - HG11617-M from Sino Biological Species Human

Human Neuroligin 1/NLGN1 Gene ORF cDNA clone expression plasmid, N-His tag - HG11617-NH from Sino Biological Species Human

Human Neuroligin 1/NLGN1 Gene ORF cDNA clone expression plasmid, C-His tag - HG11617-CH from Sino Biological Species Human

Human Neuroligin 1/NLGN1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG11617-CY from Sino Biological Species Human

Human Neuroligin 1/NLGN1 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG11617-ACR from Sino Biological Species Human

Human Neuroligin 1/NLGN1 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG11617-NF from Sino Biological Species Human

Human Neuroligin 1/NLGN1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG11617-CF from Sino Biological Species Human

Human Neuroligin 1/NLGN1 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG11617-NM from Sino Biological Species Human

Human Neuroligin 1/NLGN1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG11617-ACG from Sino Biological Species Human

Human Neuroligin 1/NLGN1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG11617-CM from Sino Biological Species Human

Human Neuroligin 1/NLGN1 Gene ORF cDNA clone expression plasmid, N-HA tag - HG11617-NY from Sino Biological Species Human

Human Neuroligin 1/NLGN1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG11617-M-M from Sino Biological Species Human

Human Neuroligin 1/NLGN1 Gene ORF cDNA clone expression plasmid - HG11617-UT from Sino Biological Species Human

Human NLGN1 ORF clone(NM_014932.2) - CDCL185489 from Creative biogene Species Human

Human NLGN1 ORF Clone (BC032555) - CDCS413830 from Creative biogene Species Human Accession Q8N2Q7

Human NLGN1 cDNA Clone(NM_014932.2) - CDFH012587 from Creative biogene Species Human

Human NLGN1 cDNA Clone(NM_014932.2) - CDFH012588 from Creative biogene Species Human

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