Gene Symbol | OSM |
---|---|
Entrez Gene | 5008 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | oncostatin M |
Other Description | oncostatin-M |
Swissprots | Q6FHP8 P13725 Q9UCP6 |
Accessions | AAA36388 AAC05173 AAD31435 EAW59864 EAW59865 P13725 AB451493 BAG70307 BC011589 AAH11589 CR456534 CAG30420 CR541703 CAG46504 CU013134 CAK54565 CU013422 CAK54864 DQ892537 ABM83463 DQ895748 ABM86674 XM_011530202 XP_011528504 NM_020530 NP_065391 |
Function | Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIPR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted. |
Top Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, PI3K-Akt signaling pathway |
OSM (E-4) - sc-365136 from Santa Cruz Biotechnology
|
||||||||||
OSM (G-1) - sc-390253 from Santa Cruz Biotechnology
|
||||||||||
OSM (H-210) - sc-50296 from Santa Cruz Biotechnology
|
||||||||||
OSM (N-1) - sc-129 from Santa Cruz Biotechnology
|
||||||||||
Anti-Oncostatin M antibody - ab198830 from Abcam
|
||||||||||
Anti-Oncostatin M antibody - ab9633 from Abcam
|
||||||||||
Anti-Oncostatin M antibody - ab110621 from Abcam
|
||||||||||
Anti-Oncostatin M antibody - ab123298 from Abcam
|
||||||||||
Anti-Oncostatin M antibody - ab131074 from Abcam
|
||||||||||
Anti-Oncostatin M antibody [17001.31] - ab10842 from Abcam
|
||||||||||
Anti-Oncostatin M antibody (Biotin) - ab84256 from Abcam
|
||||||||||
Anti-Oncostatin M antibody [EPR7150] - ab133748 from Abcam
|
||||||||||
Anti-Oncostatin M antibody [MM0499-9G21] - ab89885 from Abcam
|
||||||||||
Anti-OSM / Oncostatin M Antibody (aa26-221, clone 1D4B) - LS-C189823 from LifeSpan Bioscience
|
||||||||||
Anti-OSM / Oncostatin M Antibody (Biotin) - LS-C190400 from LifeSpan Bioscience
|
||||||||||
Anti-OSM / Oncostatin M Antibody (HRP) - LS-C211362 from LifeSpan Bioscience
|
||||||||||
Anti-OSM / Oncostatin M Antibody (FITC) - LS-C211364 from LifeSpan Bioscience
|
||||||||||
Anti-OSM / Oncostatin M Antibody (Biotin) - LS-C211365 from LifeSpan Bioscience
|
||||||||||
Anti-OSM / Oncostatin M Antibody (aa213-243, AP) - LS-C265269 from LifeSpan Bioscience
|
||||||||||
Anti-OSM / Oncostatin M Antibody (aa213-243, APC) - LS-C265270 from LifeSpan Bioscience
|
||||||||||
Anti-OSM / Oncostatin M Antibody (aa213-243, PE) - LS-C265271 from LifeSpan Bioscience
|
||||||||||
Anti-OSM / Oncostatin M Antibody (aa25-115, Biotin) - LS-C298291 from LifeSpan Bioscience
|
||||||||||
Anti-OSM / Oncostatin M Antibody (aa116-205, Biotin) - LS-C299151 from LifeSpan Bioscience
|
||||||||||
Anti-OSM / Oncostatin M Antibody (aa25-115, FITC) - LS-C301506 from LifeSpan Bioscience
|
||||||||||
Anti-OSM / Oncostatin M Antibody (aa116-205, FITC) - LS-C304733 from LifeSpan Bioscience
|