OSM

Gene Symbol	OSM
Entrez Gene	5008
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	oncostatin M
Other Description	oncostatin-M
Swissprots	Q6FHP8 P13725 Q9UCP6
Accessions	AAA36388 AAC05173 AAD31435 EAW59864 EAW59865 P13725 AB451493 BAG70307 BC011589 AAH11589 CR456534 CAG30420 CR541703 CAG46504 CU013134 CAK54565 CU013422 CAK54864 DQ892537 ABM83463 DQ895748 ABM86674 XM_011530202 XP_011528504 NM_020530 NP_065391
Function	Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIPR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration (By similarity). {ECO:0000250}.
Subcellular Location	Secreted.
Top Pathways	Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, PI3K-Akt signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-OSM-cDNA-Clone - DC03132 from Abgent, a WuXi AppTec company Prices $340.20 Sizes 10 µg Species Human Accession BC011589

OSM - MBS1272884 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC011589

Human OSM Gene cDNA clone plasmid - HG10452-M from Sino Biological Species Human

Human Oncostatin M/OSM Gene ORF cDNA clone expression plasmid, N-HA tag - HG10452-NY from Sino Biological Species Human

Human Oncostatin M/OSM Gene ORF cDNA clone expression plasmid, C-His tag - HG10452-CH from Sino Biological Species Human

Human Oncostatin M/OSM Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10452-CM from Sino Biological Species Human

Human Oncostatin M/OSM Gene ORF cDNA clone expression plasmid - HG10452-M-N from Sino Biological Species Human

Human Oncostatin M/OSM Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10452-ACR from Sino Biological Species Human

Human OSM Gene cDNA Clone (full-length ORF Clone) expression ready, FLAG-tagged - HG10452-M-F from Sino Biological Species Human Accession NM_020530.3

Human Oncostatin M/OSM Gene ORF cDNA clone expression plasmid, N-His tag - HG10452-NH from Sino Biological Species Human

Human Oncostatin M/OSM Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10452-ACG from Sino Biological Species Human

Human Oncostatin M/OSM Gene ORF cDNA clone expression plasmid - HG10452-UT from Sino Biological Species Human

Human Oncostatin M/OSM Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10452-NF from Sino Biological Species Human

Human Oncostatin M/OSM Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10452-NM from Sino Biological Species Human

Human Oncostatin M/OSM Gene ORF cDNA clone expression plasmid, C-HA tag - HG10452-CY from Sino Biological Species Human

Human Oncostatin M/OSM Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10452-CF from Sino Biological Species Human

Human OSM ORF Clone (BC011589) - CDCS415105 from Creative biogene Species Human Accession P13725

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