Gene Symbol | OSM |
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Entrez Gene | 5008 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | oncostatin M |
Other Description | oncostatin-M |
Swissprots | Q6FHP8 P13725 Q9UCP6 |
Accessions | AAA36388 AAC05173 AAD31435 EAW59864 EAW59865 P13725 AB451493 BAG70307 BC011589 AAH11589 CR456534 CAG30420 CR541703 CAG46504 CU013134 CAK54565 CU013422 CAK54864 DQ892537 ABM83463 DQ895748 ABM86674 XM_011530202 XP_011528504 NM_020530 NP_065391 |
Function | Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIPR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted. |
Top Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, PI3K-Akt signaling pathway |
OSM-Over-expression-Lysate - LY10449a from Abgent, a WuXi AppTec company
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OSM 293T Cell Transient Overexpression Lysate(Denatured) - H00005008-T01 from Acris Antibodies
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OSM 293T Cell Transient Overexpression Lysate(Denatured) - H00005008-T02 from Acris Antibodies
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OSM overexpression lysate - LY412433 from Acris Antibodies
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OSM 293 Cell Lysate - 406110 from ABBIOTEC
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Oncostatin M/OSM Overexpression Lysate (Denatured) - H00005008-T01 from Novus Biologicals
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Oncostatin M/OSM Overexpression Lysate (Denatured) - H00005008-T02 from Novus Biologicals
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Oncostatin M/OSM Overexpression Lysate (Native) - NBL1-14002 from Novus Biologicals
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OSM Over-expression Lysate Product - GWB-16CD34 from Genway Biotech
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Human Oncostatin M / OSM HEK293 Cell Lysate (WB positive control) - 10452-HNAHL-300 from Sino Biological
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Human Oncostatin M / OSM HEK293 Cell Lysate (WB positive control) - 10452-H08HL-300 from Sino Biological
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Human Oncostatin M Human Cells Transfected Lysate (positive control) (denatured) - orb232826 from Biorbyt
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Human Oncostatin M Human Cells Transfected Lysate (positive control) (denatured) - orb173951 from Biorbyt
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Panoply™ Human OSM Knockdown Stable Cell Line - CSC-DC011147 from Creative biogene
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