Gene Symbol | OSM |
---|---|
Entrez Gene | 5008 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | oncostatin M |
Other Description | oncostatin-M |
Swissprots | Q6FHP8 P13725 Q9UCP6 |
Accessions | AAA36388 AAC05173 AAD31435 EAW59864 EAW59865 P13725 AB451493 BAG70307 BC011589 AAH11589 CR456534 CAG30420 CR541703 CAG46504 CU013134 CAK54565 CU013422 CAK54864 DQ892537 ABM83463 DQ895748 ABM86674 XM_011530202 XP_011528504 NM_020530 NP_065391 |
Function | Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIPR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted. |
Top Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, PI3K-Akt signaling pathway |
Active human Oncostatin M full length protein - ab167707 from Abcam
|
||||||||||
Active human Oncostatin M full length protein - ab194155 from Abcam
|
||||||||||
Active human Oncostatin M full length protein - ab9634 from Abcam
|
||||||||||
Active human Oncostatin M full length protein - ab192091 from Abcam
|
||||||||||
Active rat Oncostatin M full length protein - ab200252 from Abcam
|
||||||||||
Human Oncostatin M full length protein - ab151857 from Abcam
|
||||||||||
Human Oncostatin M full length protein - ab109963 from Abcam
|
||||||||||
Human Oncostatin M full length protein - ab193858 from Abcam
|
||||||||||
OSM-Antibody-C-term-Blocking-Peptide - BP14525b from Abgent, a WuXi AppTec company
|
||||||||||
Oncostatin M protein - GTX29634 from GeneTex
|
||||||||||
Oncostatin M Recombinant Protein (Active) - GTX48388-PRO from GeneTex
|
||||||||||
Oncostatin M Recombinant Protein (Active) - GTX48389-PRO from GeneTex
|
||||||||||
Recombinant Human Oncostatin M (OSM) - 295-OM-010 from R&D Systems
|
||||||||||
Recombinant Human Oncostatin M (OSM) - 295-OM-050 from R&D Systems
|
||||||||||
Recombinant Human Oncostatin M (OSM), CF - 295-OM-010/CF from R&D Systems
|
||||||||||
Recombinant Human Oncostatin M (OSM), CF - 295-OM-050/CF from R&D Systems
|
||||||||||
Recombinant Human Oncostatin M (HEK-293-expressed), CF - 8475-OM-010/CF from R&D Systems
|
||||||||||
Recombinant Human Oncostatin M (HEK-293-expressed), CF - 8475-OM-050/CF from R&D Systems
|
||||||||||
Recombinant Human Oncostatin M (HEK-293-expressed) - 8475-OM-010 from R&D Systems
|
||||||||||
Recombinant Human Oncostatin M (HEK-293-expressed) - 8475-OM-050 from R&D Systems
|
||||||||||
Recombinant human Oncostatin-M (OPCA00831) - OPCA00831 from Aviva Systems Biology
|
||||||||||
Human Oncostatin M Protein (OPMA04614) - OPMA04614 from Aviva Systems Biology
|
||||||||||
OSM Protein (OPPA00496) - OPPA00496 from Aviva Systems Biology
|
||||||||||
OSM Protein (OPPA02046) - OPPA02046 from Aviva Systems Biology
|
||||||||||
ONCOSTATIN M Recombinant Protein (OPSA10973) - OPSA10973 from Aviva Systems Biology
|