OSM

Gene Symbol OSM
Entrez Gene 5008
Alt Symbol -
Species Human
Gene Type protein-coding
Description oncostatin M
Other Description oncostatin-M
Swissprots Q6FHP8 P13725 Q9UCP6
Accessions AAA36388 AAC05173 AAD31435 EAW59864 EAW59865 P13725 AB451493 BAG70307 BC011589 AAH11589 CR456534 CAG30420 CR541703 CAG46504 CU013134 CAK54565 CU013422 CAK54864 DQ892537 ABM83463 DQ895748 ABM86674 XM_011530202 XP_011528504 NM_020530 NP_065391
Function Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIPR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration (By similarity). {ECO:0000250}.
Subcellular Location Secreted.
Top Pathways Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, PI3K-Akt signaling pathway

OSM CRISPR/Cas9 KO Plasmid (h) - sc-404957 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

OSM HDR Plasmid (h) - sc-404957-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

OSM Double Nickase Plasmid (h) - sc-404957-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

OSM Double Nickase Plasmid (h2) - sc-404957-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

OSM CRISPR Activation Plasmid (h) - sc-404957-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

OSM CRISPR Activation Plasmid (h2) - sc-404957-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

OSM Lentiviral Activation Particles (h) - sc-404957-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

OSM Lentiviral Activation Particles (h2) - sc-404957-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

OSM siRNA (h) - sc-39689 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

OSM shRNA Plasmid (h) - sc-39689-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

OSM shRNA (h) Lentiviral Particles - sc-39689-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU138731 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16173 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16173 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR12464 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr12464

OSM siRNA (Human) - CRH3325 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human OSM (NM_020530.4) - SHH368788 from Creative biogene

Category siRNA
Species Reactivities Human

Human OSM siRNA - orb263827 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

OSM shRNA Plasmid (Human) - CHH3325 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

OSM miRNA 3'UTR clone - MiUTR3H-01623 from Creative biogene

Species Reactivities Human
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