NDST3

Gene Symbol	NDST3
Entrez Gene	9348
Alt Symbol	HSST3
Species	Human
Gene Type	protein-coding
Description	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
Other Description	GlcNAc N-deacetylase/ N-sulfotransferase 3|N-HSST 3|N-heparan sulfate sulfotransferase 3|NDST-3|bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3|glucosaminyl N-deacetylase/N-sulfotransferase 3|hNDST-3
Swissprots	Q4W5C1 B4DI67 Q9UP21 O95803 Q6UWC5 Q4W5D0
Accessions	AAY41001 AAY41056 EAX06313 O95803 AF074924 AAD15978 AF076605 AAD46061 AK295439 BAG58379 AY358852 AAQ89211 BC034037 BC109309 AAI09310 BC109310 AAI09311 BE348441 HQ234312 XM_006714416 XP_006714479 XM_011532414 XP_011530716 XM_011532415 XP_011530717 XM_011532416 XP_011530718 NM_004784 NP_004775
Function	Essential bifunctional enzyme that catalyzes both the N- deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Has high deacetylase activity but low sulfotransferase activity. {ECO:0000269|PubMed:9915799}.
Subcellular Location	Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Tissue Specificity	Expressed in brain, kidney, liver, fetal and adult lung, adult pancreas, placenta, fetal spleen and fetal thymus. Not detected in adult/ fetal heart and skeletal muscle. {ECO:0000269|PubMed:9915799}.
Top Pathways	Glycosaminoglycan biosynthesis - heparan sulfate / heparin

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NDST3 protein fragment - ab160446 from Abcam Category Protein Source Wheat germ Species Human

NDST3 Antibody Blocking Peptide - LS-E5232 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NDST3 Partial Recombinant Protein - H00009348-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

NDST3-Antibody-C-term-Blocking-Peptide - BP17676b from Abgent, a WuXi AppTec company Category Peptide Prices $69.00 Sizes 100 µg

NDST3 Blocking Peptide - 33R-7135 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

NDST3 - H00009348-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

NDST3 - H00009348-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

NDST3 fusion protein - ag16091 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase - CSB-YP015616HU CSB-EP015616HU CSB-BP015616HU CSB-MP015616HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

NDST3 - TP317551 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

NDST3 Recombinant Protein Antigen - NBP2-49216PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

NDST3 Peptide, Human - M34GP10225H from Creative Peptides Category Peptide Source Synthetic. Species Human

Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 (NDST3), partial, Recombinant Protein - MBS1209581 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Search more