NDST3

Gene Symbol NDST3
Entrez Gene 9348
Alt Symbol HSST3
Species Human
Gene Type protein-coding
Description N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
Other Description GlcNAc N-deacetylase/ N-sulfotransferase 3|N-HSST 3|N-heparan sulfate sulfotransferase 3|NDST-3|bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3|glucosaminyl N-deacetylase/N-sulfotransferase 3|hNDST-3
Swissprots Q4W5C1 B4DI67 Q9UP21 O95803 Q6UWC5 Q4W5D0
Accessions AAY41001 AAY41056 EAX06313 O95803 AF074924 AAD15978 AF076605 AAD46061 AK295439 BAG58379 AY358852 AAQ89211 BC034037 BC109309 AAI09310 BC109310 AAI09311 BE348441 HQ234312 XM_006714416 XP_006714479 XM_011532414 XP_011530716 XM_011532415 XP_011530717 XM_011532416 XP_011530718 NM_004784 NP_004775
Function Essential bifunctional enzyme that catalyzes both the N- deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Has high deacetylase activity but low sulfotransferase activity. {ECO:0000269|PubMed:9915799}.
Subcellular Location Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Tissue Specificity Expressed in brain, kidney, liver, fetal and adult lung, adult pancreas, placenta, fetal spleen and fetal thymus. Not detected in adult/ fetal heart and skeletal muscle. {ECO:0000269|PubMed:9915799}.
Top Pathways Glycosaminoglycan biosynthesis - heparan sulfate / heparin

NDST3 (S-14) - sc-16769 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

NDST3 (JK-3) - sc-100789 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/1.0 ml
Host Mouse
Clonality Monoclonal
NDST3 (JK-3): sc-100789. Western blot analysis of NDST3 expression in HeLa nuclear extract.

Anti-NDST3 antibody - ab85196 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-NDST3 antibody (ab85196) at 1 µg/ml (in 5% skim milk / PBS buffer) + HeLa cell lysate at 10 µgSecondaryanti-Rabbit IgG HRP at 1/50000 dilution

Anti-NDST3 antibody - ab56573 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-NDST3 antibody - ab188145 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin embedded Human kindey tissue labeling NDST3 with ab188145 at a dilution of 1/50.

Anti-NDST3 antibody - C-terminal - ab173356 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-NDST3 antibody - C-terminal (ab173356) at 1/100 dilution + HL-60 cell line lysates at 35 µg

Anti-NDST3 Antibody (aa809-836, AP) - LS-C223427 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NDST3 Antibody (aa809-836, APC) - LS-C223429 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NDST3 Antibody (aa809-836, Biotin) - LS-C223430 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NDST3 Antibody (aa809-836, FITC) - LS-C223431 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NDST3 Antibody (aa809-836, Azide-free, HRP) - LS-C223432 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NDST3 Antibody (aa809-836, PE) - LS-C223433 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NDST3 Antibody (aa216-265) - LS-C102235 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
NDST3 antibody LS-C102235 Western blot of HeLa lysate.

Anti-NDST3 Antibody (aa808-836) - LS-C323267 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NDST3 Antibody (aa162-260, Azide-free) - LS-C328009 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-NDST3 Antibody (aa809-836) - LS-C158371 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
NDST3 Antibody western blot of HL-60 cell line lysates (35 ug/lane). The NDST3 antibody detected the NDST3 protein (arrow).

NDST3 Antibody - NBP2-19501 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: NDST3 Antibody [NBP2-19501] - Sample (30 ug of whole cell lysate) A: U87-MG 5% SDS PAGE gel, diluted at 1:1000.

NDST3 Antibody - NBP1-62469 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: NDST3 Antibody [NBP1-62469] - Hela cell lysate, concentration 0.2-1 ug/ml.

NDST3 Antibody (5B9) - H00009348-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 5B9
Western Blot: NDST3 Antibody (5B9) [H00009348-M01] - NDST3 monoclonal antibody (M01), clone 5B9 Analysis of NDST3 expression in Hela S3 NE.

Anti-NDST3 antibody produced in rabbit - SAB2101559 from Sigma-Aldrich

Prices $347.50, $347.50
Sizes 50 µg, 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-NDST3: <B>Cat. No.SAB2101559</B>: NDST3 in HeLa cell lysate with NDST3 antibody at 1.0 μg/mL.

Anti-NDST3 antibody produced in rabbit - HPA056189 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-NDST3: <B>Cat. No. HPA056189</B>: Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in tubular cells.

Monoclonal Anti-NDST3 antibody produced in mouse - SAB1404707 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3A9
<B>Immunoblotting</B><BR/>Monoclonal Anti-NDST3: <B>Cat. No. SAB1404707</B>: Antibody concentration: 1 μg/mL. Specific band of ~36.9 kDa using immunogen protein lysate.

Monoclonal Anti-NDST3 antibody produced in mouse - WH0009348M1 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 5B9
<B>Immunoblotting</B><BR/>Monoclonal Anti-NDST3, <B>Cat. No. WH0009348M1</B> used at the antibody concentration: 1 ~ 5 μg/mL. Specific band of ~100.9 kDa using Hela NE lysate.

NDST3 antibody - N-terminal region (ARP46503_P050) - ARP46503_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

NDST3-Antibody-C-term - AP17676b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
NDST3 Antibody (C-term) (Cat. #AP17676b) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the NDST3 antibody detected the NDST3 protein (arrow).
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