POMP

Gene Symbol POMP
Entrez Gene 51371
Alt Symbol C13orf12, HSPC014, PNAS-110, UMP1
Species Human
Gene Type protein-coding
Description proteasome maturation protein
Other Description 2510048O06Rik|hUMP1|proteassemblin|protein UMP1 homolog|voltage-gated K channel beta subunit 4.1|voltage-gated potassium channel beta subunit 4.1
Swissprots Q9HB69 Q9Y244 D6MXU3 A5HKJ2
Accessions EAX08434 EAX08435 Q9Y244 AF077200 AAD26995 AF125097 AAD39914 AF262975 AAK58521 AF275807 AAG23819 AK312118 BAG35054 BC003390 AAH03390 BC014334 AAH14334 CD369437 DQ894129 ABM85055 EF535527 ABQ08566 GU045555 ADE92939 GU045556 ADE92940 NM_015932 NP_057016
Function Molecular chaperone essential for the assembly of standard proteasomes and immunoproteasomes. Degraded after completion of proteasome maturation. Mediates the association of 20S preproteasome with the endoplasmic reticulum. {ECO:0000269|PubMed:15944226, ECO:0000269|PubMed:16251969, ECO:0000269|PubMed:17948026}.
Subcellular Location Cytoplasm, cytosol. Nucleus. Microsome membrane.
Tissue Specificity Strongly expressed from the basal layer to the granular layer of healthy epidermis, whereas in KLICK patients there is a gradual decrease of expression toward the granular layer. {ECO:0000269|PubMed:20226437}.
Top Pathways Proteasome

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Category ELISA Kit
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Category ELISA Kit
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Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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