Gene Symbol | POMP |
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Entrez Gene | 51371 |
Alt Symbol | C13orf12, HSPC014, PNAS-110, UMP1 |
Species | Human |
Gene Type | protein-coding |
Description | proteasome maturation protein |
Other Description | 2510048O06Rik|hUMP1|proteassemblin|protein UMP1 homolog|voltage-gated K channel beta subunit 4.1|voltage-gated potassium channel beta subunit 4.1 |
Swissprots | Q9HB69 Q9Y244 D6MXU3 A5HKJ2 |
Accessions | EAX08434 EAX08435 Q9Y244 AF077200 AAD26995 AF125097 AAD39914 AF262975 AAK58521 AF275807 AAG23819 AK312118 BAG35054 BC003390 AAH03390 BC014334 AAH14334 CD369437 DQ894129 ABM85055 EF535527 ABQ08566 GU045555 ADE92939 GU045556 ADE92940 NM_015932 NP_057016 |
Function | Molecular chaperone essential for the assembly of standard proteasomes and immunoproteasomes. Degraded after completion of proteasome maturation. Mediates the association of 20S preproteasome with the endoplasmic reticulum. {ECO:0000269|PubMed:15944226, ECO:0000269|PubMed:16251969, ECO:0000269|PubMed:17948026}. |
Subcellular Location | Cytoplasm, cytosol. Nucleus. Microsome membrane. |
Tissue Specificity | Strongly expressed from the basal layer to the granular layer of healthy epidermis, whereas in KLICK patients there is a gradual decrease of expression toward the granular layer. {ECO:0000269|PubMed:20226437}. |
Top Pathways | Proteasome |
Human HSPC014 full length protein - ab162528 from Abcam
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POMP - H00051371-P01-10 from Acris Antibodies
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POMP - H00051371-P01-25 from Acris Antibodies
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POMP fusion protein - Ag6992 from Proteintech Group
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POMP fusion protein - ag6987 from Proteintech Group
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Recombinant Human POMP, His-tagged - POMP-1855H from Creative Biomart
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Recombinant Human Proteasome maturation protein(POMP) - CSB-YP018365HU CSB-EP018365HU CSB-BP018365HU CSB-MP018365HU from Cusabio
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Recombinant Proteasome Maturation Protein (POMP) - RPC731Hu01 from Cloud-clone
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Recombinant Proteasome Maturation Protein (POMP) - RPC731Hu01 from Uscn Life Science Inc.
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POMP - TP304812 from Acris Antibodies
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Proteasome maturation protein (POMP), Recombinant Protein - MBS1289672 from MyBioSource
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POMP-Blocking-Peptide-C-term - BP20420b from Abgent, a WuXi AppTec company
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POMP Recombinant Protein (OPCD06309) - OPCD06309 from Aviva Systems Biology
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Proteasome Maturation Protein, Recombinant Protein - MBS2033245 from MyBioSource
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