POMP

Gene Symbol POMP
Entrez Gene 51371
Alt Symbol C13orf12, HSPC014, PNAS-110, UMP1
Species Human
Gene Type protein-coding
Description proteasome maturation protein
Other Description 2510048O06Rik|hUMP1|proteassemblin|protein UMP1 homolog|voltage-gated K channel beta subunit 4.1|voltage-gated potassium channel beta subunit 4.1
Swissprots Q9HB69 Q9Y244 D6MXU3 A5HKJ2
Accessions EAX08434 EAX08435 Q9Y244 AF077200 AAD26995 AF125097 AAD39914 AF262975 AAK58521 AF275807 AAG23819 AK312118 BAG35054 BC003390 AAH03390 BC014334 AAH14334 CD369437 DQ894129 ABM85055 EF535527 ABQ08566 GU045555 ADE92939 GU045556 ADE92940 NM_015932 NP_057016
Function Molecular chaperone essential for the assembly of standard proteasomes and immunoproteasomes. Degraded after completion of proteasome maturation. Mediates the association of 20S preproteasome with the endoplasmic reticulum. {ECO:0000269|PubMed:15944226, ECO:0000269|PubMed:16251969, ECO:0000269|PubMed:17948026}.
Subcellular Location Cytoplasm, cytosol. Nucleus. Microsome membrane.
Tissue Specificity Strongly expressed from the basal layer to the granular layer of healthy epidermis, whereas in KLICK patients there is a gradual decrease of expression toward the granular layer. {ECO:0000269|PubMed:20226437}.
Top Pathways Proteasome

Proteassemblin CRISPR/Cas9 KO Plasmid (h) - sc-418563 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Proteassemblin HDR Plasmid (h) - sc-418563-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Proteassemblin Double Nickase Plasmid (h) - sc-418563-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Proteassemblin Double Nickase Plasmid (h2) - sc-418563-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Proteassemblin CRISPR Activation Plasmid (h) - sc-418563-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Proteassemblin CRISPR Activation Plasmid (h2) - sc-418563-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Proteassemblin Lentiviral Activation Particles (h) - sc-418563-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Proteassemblin Lentiviral Activation Particles (h2) - sc-418563-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Proteassemblin siRNA (h) - sc-62890 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Proteassemblin shRNA Plasmid (h) - sc-62890-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Proteassemblin shRNA (h) Lentiviral Particles - sc-62890-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU038291 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN17148 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17148 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06569 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr06569

POMP siRNA (Human) - CRH9728 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human POMP (NM_015932.5) - SHH379740 from Creative biogene

Category siRNA
Species Reactivities Human

Human POMP siRNA - orb270230 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

POMP shRNA Plasmid (Human) - CHH9728 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

POMP miRNA 3'UTR clone - MiUTR3H-12875 from Creative biogene

Species Reactivities Human
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