UHRF2

Gene Symbol	UHRF2
Entrez Gene	115426
Alt Symbol	NIRF, RNF107, URF2
Species	Human
Gene Type	protein-coding
Description	ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase
Other Description	E3 ubiquitin-protein ligase UHRF2|Np95-like ring finger protein|RING finger protein 107|np95/ICBP90-like RING finger protein|nuclear protein 97|nuclear zinc finger protein NP97|ubiquitin-like PHD and RING finger domain-containing protein 2|ubiquitin-like, containing PHD and RING finger domains, 2|ubiquitin-like-containing PHD and RING finger domains protein 2
Swissprots	Q5VYR1 Q659C8 Q5VYR3 Q96PU4 Q8TAG7
Accessions	EAW58743 Q96PU4 AB071698 BAB68317 AF274049 AAM33799 AK122730 BAG53694 AK308433 AL137728 CAH56383 AL833522 CAH10389 BC028397 AAH28397 BG709183 EU176286 ABW03737 EU176602 ABW03403 XM_011517703 XP_011516005 XM_011517704 XP_011516006 XM_011517705 XP_011516007 XM_011517706 XP_011516008 XR_428418 XR_428419 XR_428420 XR_428421 XR_929173 NM_152896 NP_690856 NR_046386
Function	E3 ubiquitin-protein ligase that is an intermolecular hub protein in the cell cycle network. Through cooperative DNA and histone binding, may contribute to a tighter epigenetic control of gene expression in differentiated cells. Ubiquitinates cyclins, CCND1 and CCNE1, in an apparently phosphorylation-independent manner and induces G1 arrest. Also ubiquitinates PCNP leading to its degradation by the proteasome. E3 SUMO-, but not ubiquitin-, protein ligase for ZNF131. {ECO:0000269|PubMed:12176013, ECO:0000269|PubMed:14741369, ECO:0000269|PubMed:15178429, ECO:0000269|PubMed:15361834, ECO:0000269|PubMed:21952639, ECO:0000269|PubMed:23404503}.
Subcellular Location	Nucleus {ECO:0000255|PROSITE- ProRule:PRU00358, ECO:0000269|PubMed:12176013, ECO:0000269|PubMed:23404503}. Note=Enriched at pericentric heterochromatin (PH). This localization is dependent on the interaction with H3K9me3 (By similarity). {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• Cell/Tissue/Blood Products

E3 ubiquitin-protein ligase UHRF2, UHRF2, ELISA Kit - MBS2602716 from MyBioSource Category ELISA Kit Prices $275.00, $420.00, $1,615.00, $2,880.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.06 ng/ml. Range 20 ng/ml-0.312 ng/ml

Human UHRF2 ELISA Kit - E012659 from Biobool Category ELISA Kit Sensitivity 0.06 ng/ml.

E3 ubiquitin-protein ligase UHRF2 (UHRF2), ELISA Kit - MBS2610241 from MyBioSource Category ELISA Kit Prices $300.00, $475.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

E3 ubiquitin-protein ligase UHRF2, ELISA Kit - MBS2605220 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

E3 ubiquitin-protein ligase UHRF2, ELISA Kit - MBS2605809 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

E3 ubiquitin-protein ligase UHRF2 , ELISA Kit - MBS2605399 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

E3 ubiquitin-protein ligase UHRF2, ELISA Kit - MBS2608296 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

E3 ubiquitin-protein ligase UHRF2, ELISA Kit - MBS2605477 from MyBioSource Category ELISA Kit Prices $275.00, $420.00, $1,615.00, $2,880.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

E3 ubiquitin-protein ligase UHRF2, ELISA Kit - MBS2603950 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

E3 ubiquitin-protein ligase UHRF2, ELISA Kit - MBS2603569 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

E3 ubiquitin-protein ligase UHRF2, ELISA Kit - MBS2607688 from MyBioSource Category ELISA Kit Prices $290.00, $450.00, $1,755.00, $3,150.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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