FSTL3

Gene Symbol FSTL3
Entrez Gene 10272
Alt Symbol FLRG, FSRP
Species Human
Gene Type protein-coding
Description follistatin-like 3 (secreted glycoprotein)
Other Description follistatin-like protein 3|follistatin-related gene protein|follistatin-related protein 3
Swissprots A8K7E3 O95633
Accessions EAW61165 EAW61166 O95633 AK291958 BAF84647 AK311521 AK311566 AK313341 AL050194 AY358917 AAQ89276 BC005839 AAH05839 BC033119 BQ319646 BX439786 U76702 AAC64321 NM_005860 NP_005851
Function Isoform 1 or the secreted form is a binding and antagonizing protein for members of the TGF-beta family, such us activin, BMP2 and MSTN. Inhibits activin A-, activin B-, BMP2- and MSDT-induced cellular signaling; more effective on activin A than on activin B. Involved in bone formation; inhibits osteoclast differentiationc. Involved in hematopoiesis; involved in differentiation of hemopoietic progenitor cells, increases hematopoietic cell adhesion to fibronectin and seems to contribute to the adhesion of hematopoietic precursor cells to the bone marrow stroma. Isoform 2 or the nuclear form is probably involved in transcriptional regulation via interaction with MLLT10. {ECO:0000269|PubMed:11948405, ECO:0000269|PubMed:15451575, ECO:0000269|PubMed:15574124, ECO:0000269|PubMed:16336961, ECO:0000269|PubMed:17868029, ECO:0000269|PubMed:17878677}.
Subcellular Location Isoform 1: Secreted.
Tissue Specificity Expressed in a wide range of tissues. {ECO:0000269|PubMed:11459787}.

FLRG CRISPR/Cas9 KO Plasmid (h) - sc-406439 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FLRG HDR Plasmid (h) - sc-406439-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FLRG Double Nickase Plasmid (h) - sc-406439-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FLRG Double Nickase Plasmid (h2) - sc-406439-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FLRG CRISPR Activation Plasmid (h) - sc-406439-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FLRG CRISPR Activation Plasmid (h2) - sc-406439-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FLRG Lentiviral Activation Particles (h) - sc-406439-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FLRG Lentiviral Activation Particles (h2) - sc-406439-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FLRG siRNA (h) - sc-39760 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FLRG shRNA Plasmid (h) - sc-39760-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FLRG shRNA (h) Lentiviral Particles - sc-39760-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU008811 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN8972 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8972 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09960 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr09960

FSTL3 siRNA (Human) - CRH6954 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FSTL3 - MBS8239493 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FLRG CRISPR/Cas9 KO Plasmid (h2) - sc-406439-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FLRG HDR Plasmid (h2) - sc-406439-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human FSTL3 (NM_005860.2) - SHH297445 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human FSTL3(NM_005860.2) - SHH069329 from Creative biogene

Category siRNA
Species Reactivities Human

Human FSTL3 siRNA - orb267456 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FSTL3 shRNA Plasmid (Human) - CHH6954 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

FSTL3 miRNA 3'UTR clone - MiUTR1H-03863 from Creative biogene

Species Reactivities Human
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