SRRM1

Gene Symbol SRRM1
Entrez Gene 10250
Alt Symbol 160-KD, POP101, SRM160
Species Human
Gene Type protein-coding
Description serine/arginine repetitive matrix 1
Other Description SR-related nuclear matrix protein of 160 kDa|Ser/Arg-related nuclear matrix protein|serine/arginine repetitive matrix protein 1
Swissprots Q5VVN4 O60585 Q8IYB3
Accessions EAW95138 EAW95139 EAW95140 Q8IYB3 AA744578 AF048977 AAC09321 AF419855 AAP97290 AK293576 BAG57046 AK302498 BAH13726 AK307419 AK307568 AW958761 BC011019 BC017315 BC036187 AAH36187 BC107072 BG178896 BG720378 CX782666 DC353932 XM_005245717 XP_005245774 XM_005245718 XP_005245775 XM_005245720 XP_005245777 XM_005245721 XP_005245778 XM_005245722 XP_005245779 XM_011540478 XP_011538780 XM_011540479 XP_011538781 XM_011540480 XP_011538782 XM_011540481 XP_011538783 XM_011540482 XP_011538784 XM_011540483 XP_011538785 XR_241183 NM_001303448 NP_001290377 NM_001303449 NP_001290378 NM_005839 NP_005830
Function Part of pre- and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging together sequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3'-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with low sequence specificity and has similar preference for either double- or single-stranded nucleic acid substrates. {ECO:0000269|PubMed:10339552, ECO:0000269|PubMed:10668804, ECO:0000269|PubMed:11739730, ECO:0000269|PubMed:12600940, ECO:0000269|PubMed:12944400, ECO:0000269|PubMed:9531537}.
Subcellular Location Nucleus matrix. Nucleus speckle.
Top Pathways RNA transport, mRNA surveillance pathway

SRm160 (E-8) - sc-398789 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SRm160 (E-8): sc-398789. Western blot analysis of SRm160 expression in HeLa (A), Jurkat (B) and KNRK (C) whole cell lysates.

SRm160 (K-15) - sc-10989 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SRm160 (K-15): sc-10989. Western blot analysis of SRm160 expression in HeLa (A) and KNRK (B) whole cell lysates.

SRm160 (C-15) - sc-10990 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

SRm160 (H-180) - sc-28723 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-SRRM1 Antibody - LS-C17912 from LifeSpan Bioscience

Prices $325.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-SRRM1 Antibody (aa771-820) - LS-C145691 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
SRRM1 antibody LS-C145691 Western blot of Rat Brain lysate. Antibody concentration 1 ug/ml.

Anti-SRRM1 Antibody - LS-C334502 from LifeSpan Bioscience

Prices $315.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using SRRM1 antibody.

SRRM1 Antibody - NBP2-13381 from Novus Biologicals

Prices $129.00, $419.00
Sizes 25 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SRRM1 Antibody [NBP2-13381] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10. Lane 2: NTERA-2 High

SRRM1 Polyclonal Antibody - bs-8066R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SRRM1 antibody produced in rabbit - HPA049941 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SRRM1:<B>Cat. No. HPA049941</B>: Immunohistochemical staining of human colon shows strong nuclear positivity in glandular cells.

Anti-SRRM1 antibody produced in rabbit - S3320 from Sigma-Aldrich

Prices $445.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

SRRM1 antibody - 70R-20530 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

SRRM1 Polyclonal Antibody - A4393 from ABclonal

Prices $200.00, $480.00
Sizes 50 µg, 200 µg
Host Rabbit
Clonality Polyclonal

SRRM1 Polyclonal Antibody - A6066 from ABclonal

Prices $130.00, $220.00, $380.00
Sizes 50 µl, 100 µl, 200 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using SRRM1 antibody.

SRRM1 Antibody - abx003275 from Abbexa

Host Rabbit
Clonality Polyclonal

SRRM1 Antibody - abx004669 from Abbexa

Host Rabbit
Clonality Polyclonal

SRRM1 / SRM160 antibody - 12822-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Mouse liver were subjected to SDS PAGE followed by western blot with 12822-1-AP(SRRM1 Antibody) at dilution of 1:600

Anti-SRRM1, Polyclonal Antibody - 25-A4393 from ARP American Research Products

Prices $379.00, $549.00
Sizes 100 µg, 200 µg
Host Rabbit
Clonality Polyclonal

Anti-SRRM1, Polyclonal Antibody - 25-A6066 from ARP American Research Products

Prices $279.00, $549.00
Sizes 50 µg, 200 µg
Host Rabbit
Clonality Polyclonal

SRRM1 antibody - STJ25699 from St John's Laboratory Ltd

Host Rabbit
Clonality Polyclonal

Anti-SRRM1 antibody - STJ27860 from St John's Laboratory Ltd

Host Rabbit
Clonality Polyclonal

SRRM1 antibody - 12822-1-AP from Proteintech Group

Prices $279.00
Sizes con: 45 μg/150μl
Host Rabbit
Clonality Polyclonal
mouse liver tissue were subjected to SDS PAGE followed by western blot with 12822-1-AP(SRRM1 antibody) at dilution of 1:500

SRRM1 - MBS129456 from MyBioSource

Prices $285.00, $555.00
Sizes 50 µg, 200 µg
Host Rabbit
Clonality Polyclonal

SRRM1 - MBS9126338 from MyBioSource

Prices $305.00, $460.00, $685.00
Sizes 50 µg, 100 µg, 200 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using SRRM1 antibody.

SRRM1 - A6066 from NeoScientific

Prices $380.00, $620.00
Sizes 100 µl, 200 µl
Host Rabbit
Clonality Polyclonal
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