MUC16

Gene Symbol	MUC16
Entrez Gene	94025
Alt Symbol	CA125
Species	Human
Gene Type	protein-coding
Description	mucin 16, cell surface associated
Other Description	CA125 ovarian cancer antigen|mucin-16|ovarian cancer-related tumor marker CA125|ovarian carcinoma antigen CA125
Swissprots	Q6ZQW5 Q96RK2 Q8WXI7
Accessions	Q8WXI7 AF361486 AAK74120 AF414442 AAL65133 AK024365 BAB14899 AK056791 AK128681 BAC87568 AK128856 BAG54742 AK128857 BAG54743 AM903345 CAP17281 BF359193 BI256451 NM_024690 NP_078966
Function	Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. {ECO:0000250}.
Subcellular Location	Cell membrane; Single-pass type I membrane protein. Secreted, extracellular space. Note=May be liberated into the extracellular space following the phosphorylation of the intracellular C-terminus which induces the proteolytic cleavage and liberation of the extracellular domain.
Tissue Specificity	Expressed in corneal and conjunctival epithelia (at protein level). Overexpressed in ovarian carcinomas and ovarian low malignant potential (LMP) tumors as compared to the expression in normal ovarian tissue and ovarian adenomas. {ECO:0000269|PubMed:11369781, ECO:0000269|PubMed:12218296, ECO:0000269|PubMed:16384952}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MUC16 protein fragment - ab164957 from Abcam Category Protein Source Wheat germ Species Human

MUC16 peptide - ab139976 from Abcam Category Peptide

MUC16 / CA125 Antibody Blocking Peptide - LS-E27756 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MUC16 / CA125 Antibody Blocking Peptide - LS-E27336 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CA125/MUC16 Partial Recombinant Protein - H00094025-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

CA125 blocking peptide - GTX88166-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

Recombinant Human CA125/MUC16, CF - 5609-MU-050 from R&D Systems Category Protein Source Chinese Hamster Ovary cell line, CHO-derived, Met21005-Gln21992 (His21384Pro, Ser21487Cys, & Leu21691Pro) with a C-terminal 6-His tag

Recombinant human Mucin-16 protein (OPCA00883) - OPCA00883 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Human

Human CA125 Calibrator Grade (OPMA00001) - OPMA00001 from Aviva Systems Biology Category Protein Prices $225.00 Sizes 50 ku Species Human

Human CA125 Calib. Grade LCR Protein (OPMA04169) - OPMA04169 from Aviva Systems Biology Category Protein Prices $395.00 Sizes 50 ku Source Cell culture supernatant Species Human

Human CA125 LCR Calib. Grade Protein (OPMA04172) - OPMA04172 from Aviva Systems Biology Category Protein Prices $395.00 Sizes 50 ku Source Human pleural fluids Species Human

CA125 LCR Calib. Grade (50KU) Protein (OPMA04232) - OPMA04232 from Aviva Systems Biology Category Protein Prices $395.00 Sizes 50 ku Species Human

Human CA125 LCR Calib. Grade Protein (OPMA04349) - OPMA04349 from Aviva Systems Biology Category Protein Prices $590.00 Sizes 250 ku Species Human

Human CA125 Antigen Grade Protein (OPMA04376) - OPMA04376 from Aviva Systems Biology Category Protein Prices $450.00 Sizes 50 ku Source Ovarian carcinoma cell line Species Human

Human MUC16 protein - orb245473 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

CA125 protein - orb79650 from Biorbyt Category Protein Prices $638.00 Sizes 250 kiu

CA125 peptide - orb72411 from Biorbyt Category Peptide Prices $238.00 Sizes 500 µg

Goat anti Muc16 antibody Immunizing peptide - orb66275 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

CA 125 protein - 30-AC11 from Fitzgerald Category Protein Prices $489.50 Sizes 20 ku

CA 125 protein - 30C-CP9062 from Fitzgerald Category Protein Prices $295.00 Sizes 25 ku

CA 125 protein - 30-1070 from Fitzgerald Category Protein Prices $445.00 Sizes 10 ku Species Human

CA 125 protein - 30C-CP1062 from Fitzgerald Category Protein Prices $75.00, $95.00 Sizes 5 ku, 10 ku

CA 125 protein - 30-AC21 from Fitzgerald Category Protein Prices $346.50 Sizes 50 ku

CA 125 protein - 30-AC20S from Fitzgerald Category Protein Prices $290.00 Sizes 50 ku Species Human

CA 125 protein - 30C-CP1062P from Fitzgerald Category Protein Prices $195.00 Sizes 25 ku

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