Gene Symbol | MUC16 |
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Entrez Gene | 94025 |
Alt Symbol | CA125 |
Species | Human |
Gene Type | protein-coding |
Description | mucin 16, cell surface associated |
Other Description | CA125 ovarian cancer antigen|mucin-16|ovarian cancer-related tumor marker CA125|ovarian carcinoma antigen CA125 |
Swissprots | Q6ZQW5 Q96RK2 Q8WXI7 |
Accessions | Q8WXI7 AF361486 AAK74120 AF414442 AAL65133 AK024365 BAB14899 AK056791 AK128681 BAC87568 AK128856 BAG54742 AK128857 BAG54743 AM903345 CAP17281 BF359193 BI256451 NM_024690 NP_078966 |
Function | Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. {ECO:0000250}. |
Subcellular Location | Cell membrane; Single-pass type I membrane protein. Secreted, extracellular space. Note=May be liberated into the extracellular space following the phosphorylation of the intracellular C-terminus which induces the proteolytic cleavage and liberation of the extracellular domain. |
Tissue Specificity | Expressed in corneal and conjunctival epithelia (at protein level). Overexpressed in ovarian carcinomas and ovarian low malignant potential (LMP) tumors as compared to the expression in normal ovarian tissue and ovarian adenomas. {ECO:0000269|PubMed:11369781, ECO:0000269|PubMed:12218296, ECO:0000269|PubMed:16384952}. |
CA125 (MUC16) Human SimpleStep ELISA™ Kit - ab195213 from Abcam
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Cancer Antigen CA125 Human ELISA Kit - ab108653 from Abcam
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Human MUC16 / CA125 ELISA Kit (Sandwich ELISA) - LS-F5208 from LifeSpan Bioscience
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Mouse MUC16 / CA125 ELISA Kit (Sandwich ELISA) - LS-F4087 from LifeSpan Bioscience
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Human MUC16 / CA125 ELISA Kit (Sandwich ELISA) - LS-F428 from LifeSpan Bioscience
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Human MUC16 / CA125 ELISA Kit (Sandwich ELISA) - LS-F10001 from LifeSpan Bioscience
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Human Carbohydrate Antigen 125 / Mucin-16 ELISA Kit - RAB0376 from Sigma-Aldrich
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CA-125 ELISA Kit - SE120017 from Sigma-Aldrich
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Human CA125/MUC16 Quantikine ELISA Kit - DCA125 from R&D Systems
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Quantikine Immunoassay Control Set 765 for Human CA125/MUC16 - QC56 from R&D Systems
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Human CA125/MUC16 DuoSet ELISA - DY5609-05 from R&D Systems
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CA 125 ELISA kit - 55R-2216 from Fitzgerald
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Human CA125 ELISA Kit - abx150879 from Abbexa
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Carbohydrate Antigen 125 (CA125), Human, ELISA Kit - SEA154Hu from ARP American Research Products
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Carbonhyde Antigen 125 (CA125), Human, ELISA Kit - E01C2347 from ARP American Research Products
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Carbonhydrate Antigen 125 (CA125), Human, ELISA Kit - CSB-E04771h from ARP American Research Products
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Mucin-16, MUC16, Human, ELISA Kit - E0154h from ARP American Research Products
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Carbohydrate Antigen 125, CA125, Human, ELISA Kit - E-EL-H0636 from ARP American Research Products
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Carbohydrate Antigen 125, CA125, Mouse, ELISA Kit - E-EL-M0870 from ARP American Research Products
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Carbohydrate Antigen 125, CA125, Rat, ELISA Kit - E-EL-R0707 from ARP American Research Products
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Carbohydrate Antigen 125, CA125, Rabbit, ELISA Kit - E-EL-RB0543 from ARP American Research Products
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Carbohydrate Antigen 125, CA125, Chicken, ELISA Kit - E-EL-Ch0083 from ARP American Research Products
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Carbohydrate Antigen 125, CA125, Porcine, ELISA Kit - E-EL-P1765 from ARP American Research Products
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Carbohydrate Antigen 125, CA125, Guinea Pig, ELISA Kit - E-EL-GP0776 from ARP American Research Products
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Carbohydrate Antigen 125, CA125, Monkey, ELISA Kit - E-EL-MK2142 from ARP American Research Products
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