SLC22A16

Gene Symbol SLC22A16
Entrez Gene 85413
Alt Symbol CT2, FLIPT2, OAT6, OCT6, OKB1, dJ261K5.1
Species Human
Gene Type protein-coding
Description solute carrier family 22 (organic cation/carnitine transporter), member 16
Other Description WUGSC:RG331P03.1|carnitine transporter 2|flipt 2|fly-like putative organic ion transporter 2|fly-like putative transporter 2|organic cation transporter 6|organic cation transporter OKB1|organic cation/carnitine transporter 6|solute carrier family 22 (organic cation transporter), member 16|solute carrier family 22 member 16
Swissprots Q8IUG8 Q5JXM1 Q96M90 Q8IZD5 O14567 Q86VW1 Q96RU0
Accessions AAB67044 EAW48313 EAW48314 EAW48315 Q86VW1 AB055798 BAC23062 AF268892 AAK58593 AI632467 AK057306 BAB71419 AK304546 BAG65342 AY145502 AAN52928 BC012014 AAH12014 BC037247 BC047565 AAH47565 JF432782 ADZ15999 XM_005267184 XP_005267241 XM_011536204 XP_011534506 XM_011536205 XP_011534507 XM_011536206 XP_011534508 XM_011536207 XP_011534509 XM_011536208 XP_011534510 XM_011536209 XP_011534511 XM_011536210 XP_011534512 XM_011536211 XP_011534513 XM_011536212 XP_011534514 NM_033125 NP_149116
Function High affinity carnitine transporter; the uptake is partially sodium-ion dependent. Thought to mediate the L-carnitine secretion mechanism from testis epididymal epithelium into the lumen which is involved in the maturation of spermatozoa. Also transports organic cations such as tetraethylammonium (TEA) and doxorubicin. The uptake of TEA is inhibited by various organic cations. The uptake of doxorubicin is sodium-independent. {ECO:0000269|PubMed:12089149, ECO:0000269|PubMed:15963465}.
Subcellular Location Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Cell membrane {ECO:0000269|PubMed:12089149}. Note=Detected in the plasma membrane of Sertoli cells and in the luminal membrane of epithelial cells in the epididymis.
Tissue Specificity Widely expressed at low levels in adult tissues and fetal brain, lung, liver and kidney. Expressed in testis and epididymis (at protein level). Expressed at lower levels in bone marrow and fetal liver. Expressed in hematopoietic cells, including CD34(+) leukocytes and leukemia cells. Abundantly expressed in ovarian cancer clear-cell adenocarcinoma. Expressed in endometrium (at protein level); highly expressed during the normal secretory phase, but expression is significantly reduced in the proliferative phase. {ECO:0000269|PubMed:12089149, ECO:0000269|PubMed:12372408, ECO:0000269|PubMed:12384147, ECO:0000269|PubMed:15963465, ECO:0000269|PubMed:17197897, ECO:0000269|PubMed:17581421}.

OCT6 (E-12) - sc-132395 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
OCT6 (E-12): sc-132395. Western blot analysis of OCT6 expression in Hep G2 whole cell lysate.

OCT6 (H-113) - sc-292102 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

OCT6 (S-14) - sc-132398 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
OCT6 (S-14): sc-132398. Western blot analysis of OCT6 expression in U-87 MG (A), Hep G2 (B) and NCI-H460 (C) whole cell lysates.

OCT6 (H-6) - sc-390056 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
OCT6 (H-6): sc-390056. Western blot analysis of OCT6 expression in Jurkat (A), CCRF-CEM (B), AML-193 (C) and ALL-SIL (D) whole cell lysates.

OCT6 (A-22) - sc-102046 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
OCT6 (A-22): sc-102046. Western blot analysis of OCT6 expression in Hep G2 whole cell lysate.

Anti-SLC22A16 antibody - ab58594 from Abcam

Prices $242.00
Sizes 200 µl
Host Goat
Clonality Polyclonal

Anti-SLC22A16 Antibody (aa101-150) IHC-plus™ - LS-B11472 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-SLC22A16 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-SLC22A16 Antibody (aa67-78) - LS-C55473 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-SLC22A16 Antibody (aa97-110) - LS-C205062 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-POU3F1 / OCT6 Antibody (Ala332) - LS-C176922 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of Oct-6 (A332) pAb in extracts from A549 cell.

SLC22A16 Antibody - NBP1-85411 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SLC22A16 Antibody [NBP1-85411] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10Lane 2: Testis

SLC22A16 Antibody - NBP1-85410 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: SLC22A16 Antibody [NBP1-85410] - Staining of human duodenum shows moderate cytoplasmic positivity in glandular cells.

SLC22A16 Antibody - NBP1-60040 from Novus Biologicals

Prices $299.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SLC22A16 Antibody [NBP1-60040] - HepG2 cell lysate, Antibody Titration: 2.5ug/ml

SLC22A16 Antibody - NB100-55400 from Novus Biologicals

Prices $229.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Immunohistochemistry-Paraffin: SLC22A16 Antibody [NB100-55400] - (4ug/ml) staining of paraffin embedded Human Testis. Microwaved antigen retrieval with Tris/EDTA buffer pH9, HRP-staining.

Anti-SLC22A16 antibody produced in rabbit - HPA036903 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SLC22A16: <B>Cat. No. HPA036903</B>: Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in exocrine pancreas.

Anti-SLC22A16 antibody produced in rabbit - HPA036902 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SLC22A16: <B>Cat. No. HPA036902</B>: Immunohistochemical staining of human duodenum shows moderate cytoplasmic positivity in glandular cells.

SLC22A16 antibody - N-terminal region (ARP44073_T100) - ARP44073_T100 from Aviva Systems Biology

Prices $229.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SLC22A16-Antibody-internal-region - AF2542a from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

SLC22A16-aa97-110-Antibody-internal-region - AF3642a from Abgent, a WuXi AppTec company

Prices $325.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

SLC22A16 Antibody (OAEB00101) - OAEB00101 from Aviva Systems Biology

Prices $229.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Goat anti-SLC22A16 (aa97-110) middle region Antibody (OAEB02891) - OAEB02891 from Aviva Systems Biology

Prices $229.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

SLC22A16 antibody - 70R-1824 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

SLC22A16 antibody - H00085413-B01P from Acris Antibodies

Prices $1,530.00
Sizes 500 µg
Host Mouse
Clonality Polyclonal

Anti-SLC22A16 Antibody - AC11-0423 from Abcore

Prices $325.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-SLC22A16 Antibody - AC11-0424 from Abcore

Prices $325.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
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