RALB

Gene Symbol	RALB
Entrez Gene	5899
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	v-ral simian leukemia viral oncogene homolog B
Other Description	RAS-like protein B|ras related GTP binding protein B|ras-related protein Ral-B|v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)
Swissprots	B4E040 P11234 Q6ZS74 Q53T32
Accessions	AAY14800 EAW95240 EAW95241 EAW95242 P11234 AF493911 AAM12625 AK127675 BAC87080 AK303214 BAG64302 AK304588 BAG65376 AK312453 BAG35360 BC018163 AAH18163 BQ893549 BT006953 AAP35599 JF432766 ADZ15983 M35416 AAA60250 X15015 CAA33119 XM_005263724 XP_005263781 XM_005263727 XP_005263784 XM_005263728 XP_005263785 XM_005263729 XP_005263786 XM_011511573 XP_011509875 XM_011511574 XP_011509876 NM_002881 NP_002872
Function	Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Required both to stabilize the assembly of the exocyst complex and to localize functional exocyst complexes to the leading edge of migrating cells. Plays a role in the late stages of cytokinesis and is required for the abscission of the bridge joining the sister cells emerging from mitosis. Required for suppression of apoptosis. {ECO:0000269|PubMed:18756269}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:17875936, ECO:0000269|PubMed:18756269}; Lipid-anchor {ECO:0000269|PubMed:17875936, ECO:0000269|PubMed:18756269}; Cytoplasmic side {ECO:0000269|PubMed:17875936, ECO:0000269|PubMed:18756269}. Note=During late cytokinesis localizes at the midbody.
Top Pathways	Pancreatic cancer, Rap1 signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

RALB-Over-expression-Lysate - LY15320a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

RALB 293T Cell Transient Overexpression Lysate(Denatured) - H00005899-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

RALB 293 Cell Lysate - 408910 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg Species Monkey Disease Cancer

RalB Overexpression Lysate (Denatured) - H00005899-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

RalB Overexpression Lysate (Native) - NBL1-15131 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

RALB Over-expression Lysate Product - GWB-D89FBB from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Panoply™ Human RALB Knockdown Stable Cell Line - CSC-DC012935 from Creative biogene Category Cell Line Species Human

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