RALB

Gene Symbol	RALB
Entrez Gene	5899
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	v-ral simian leukemia viral oncogene homolog B
Other Description	RAS-like protein B|ras related GTP binding protein B|ras-related protein Ral-B|v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)
Swissprots	B4E040 P11234 Q6ZS74 Q53T32
Accessions	AAY14800 EAW95240 EAW95241 EAW95242 P11234 AF493911 AAM12625 AK127675 BAC87080 AK303214 BAG64302 AK304588 BAG65376 AK312453 BAG35360 BC018163 AAH18163 BQ893549 BT006953 AAP35599 JF432766 ADZ15983 M35416 AAA60250 X15015 CAA33119 XM_005263724 XP_005263781 XM_005263727 XP_005263784 XM_005263728 XP_005263785 XM_005263729 XP_005263786 XM_011511573 XP_011509875 XM_011511574 XP_011509876 NM_002881 NP_002872
Function	Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Required both to stabilize the assembly of the exocyst complex and to localize functional exocyst complexes to the leading edge of migrating cells. Plays a role in the late stages of cytokinesis and is required for the abscission of the bridge joining the sister cells emerging from mitosis. Required for suppression of apoptosis. {ECO:0000269|PubMed:18756269}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:17875936, ECO:0000269|PubMed:18756269}; Lipid-anchor {ECO:0000269|PubMed:17875936, ECO:0000269|PubMed:18756269}; Cytoplasmic side {ECO:0000269|PubMed:17875936, ECO:0000269|PubMed:18756269}. Note=During late cytokinesis localizes at the midbody.
Top Pathways	Pancreatic cancer, Rap1 signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human RALB (mutated Q72 L) full length protein - ab176674 from Abcam Category Protein Source E. coli Species Human

Human RALB full length protein - ab133005 from Abcam Category Protein Source Wheat germ Species Human

Human RALB full length protein - ab133006 from Abcam Category Protein Source Wheat germ Species Human

Human RALB full length protein - ab102696 from Abcam Category Protein Source E. coli Species Human

Human RALB full length protein - ab176672 from Abcam Category Protein Source E. coli Species Human

Human RALB protein fragment - ab159308 from Abcam Category Protein Source Wheat germ Species Human

RALB Antibody Blocking Peptide - LS-E20525 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RALB Antibody Blocking Peptide - LS-E20526 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RalB Recombinant Protein - H00005899-P02 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

RalB Partial Recombinant Protein - H00005899-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

RalB Recombinant Protein - H00005899-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human RalB Protein - NBP1-50923 from Novus Biologicals Category Protein Prices $349.00, $969.00 Sizes 50 µg, 250 µg Source E.coli Species Human

RALB Protein - GTX109101-pro from GeneTex Category Protein Prices $299.00 Sizes 25 μg Source E. coli Species Human

RALB Protein (OPPA02622) - OPPA02622 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 2 µg Source E. Coli

Human RALB protein - orb169158 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Species Human

RALB Blocking Peptide - 33R-3044 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

RALB protein (His tag) - 80R-1599 from Fitzgerald Category Protein Prices $340.00 Sizes 50 µg Source E.coli

RALB Blocking Peptide - abx063180 from Abbexa Category Peptide Species Human, Mouse, Rat, Monkey

RALB - AR00160PU-N from Acris Antibodies Category Protein Prices $380.00 Sizes 25 µg Species Human

RALB (1-203, His-tag) - AR09779PU-L from Acris Antibodies Category Protein Prices $1,020.00 Sizes 250 µg Source E. coli Species Human

RALB (1-203, His-tag) - AR09779PU-N from Acris Antibodies Category Protein Prices $420.00 Sizes 50 µg Source E. coli Species Human

RALB - H00005899-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

RALB - H00005899-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

RALB - H00005899-P02 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

RALB - H00005899-P02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

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