RALB

Gene Symbol RALB
Entrez Gene 5899
Alt Symbol -
Species Human
Gene Type protein-coding
Description v-ral simian leukemia viral oncogene homolog B
Other Description RAS-like protein B|ras related GTP binding protein B|ras-related protein Ral-B|v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)
Swissprots B4E040 P11234 Q6ZS74 Q53T32
Accessions AAY14800 EAW95240 EAW95241 EAW95242 P11234 AF493911 AAM12625 AK127675 BAC87080 AK303214 BAG64302 AK304588 BAG65376 AK312453 BAG35360 BC018163 AAH18163 BQ893549 BT006953 AAP35599 JF432766 ADZ15983 M35416 AAA60250 X15015 CAA33119 XM_005263724 XP_005263781 XM_005263727 XP_005263784 XM_005263728 XP_005263785 XM_005263729 XP_005263786 XM_011511573 XP_011509875 XM_011511574 XP_011509876 NM_002881 NP_002872
Function Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Required both to stabilize the assembly of the exocyst complex and to localize functional exocyst complexes to the leading edge of migrating cells. Plays a role in the late stages of cytokinesis and is required for the abscission of the bridge joining the sister cells emerging from mitosis. Required for suppression of apoptosis. {ECO:0000269|PubMed:18756269}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:17875936, ECO:0000269|PubMed:18756269}; Lipid-anchor {ECO:0000269|PubMed:17875936, ECO:0000269|PubMed:18756269}; Cytoplasmic side {ECO:0000269|PubMed:17875936, ECO:0000269|PubMed:18756269}. Note=During late cytokinesis localizes at the midbody.
Top Pathways Pancreatic cancer, Rap1 signaling pathway

RalB Antibody - 3523 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell types using RalB Antibody.

Ral B (C-8) - sc-390108 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Ral B (C-8): sc-390108. Western blot analysis of Ral B expression in non-transfected: sc-117752 (A) and mouse Ral B transfected: sc-122953 (B) 293T whole cell lysates.

Ral B (R-19) - sc-1531 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Ral B (R-19): sc-1531. Western blot analysis of Ral B expression in non-transfected: sc-117752 (A) and mouse Ral B transfected: sc-122953 (B) 293T whole cell lysates.

Ral B (XY-12) - sc-81927 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
Ral B (XY-12): sc-81927. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human colon tissue showing membrane and cytoplasmic localization.

Anti-RALB antibody - ab96456 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-RALB antibody (ab96456) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

Anti-RALB antibody - ab182758 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-RALB antibody (ab182758) at 1/250 dilution + Mouse lung tissue at 30 µgSecondaryGoat anti Rabbit IgG - H&L (HRP) at 1/3000 dilutiondeveloped using the ECL technique

Anti-RalB antibody - ab192363 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-RalB antibody (ab192363)Lane 1 : A549 whole cell lysateLane 2 : NIH 3T3 whole cell lysateLane 3 : PC12 whole cell lysate

Anti-RALB antibody - ab170044 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-RALB antibody (ab170044) at 1/100 dilution + EC-1 cell lysate.

Anti-RALB antibody - ab88451 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-RALB antibody (ab88451) at 1 µg/ml + Human placenta tissue at 25 µgSecondaryGoat Anti-Mouse IgG at 1/2500 dilutionObserved band size : 23 kDa (why is the actual band size different from the predicted?)

Anti-RALB antibody - ab102093 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-RALB antibody (ab102093) at 1 µg/ml + ACHN cell lysate at 10 µg

Anti-RALB antibody - ab157536 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-RALB antibody (ab157536) at 1 µg/ml + Mouse testis lysate at 10 µg

Anti-RALB antibody [2C4] - ab156799 from Abcam

Prices $384.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2C4
All lanes : Anti-RALB antibody [2C4] (ab156799) at 1/200 dilutionLane 1 : HEK293T cells transfected with pCMV6-ENTRY control cDNALane 2 : HEK293T cells transfected with pCMV6-ENTRY RALB cDNALysates/proteins at 5 µg per lane.

Anti-RALB antibody [4D1] - ab117742 from Abcam

Prices $384.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 4D1
All lanes : Anti-RALB antibody [4D1] (ab117742)Lane 1 : 293T cell lysate, transfected with RALBLane 2 : 293T cell lysate, non-transfected

Anti-RALB antibody [EPR6471] - ab129077 from Abcam

Prices $99.00, $379.00
Sizes 10 µl, 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6471
All lanes : Anti-RALB antibody [EPR6471] (ab129077) at 1/1000 dilutionLane 1 : HepG2 cell lysateLane 2 : 293T cell lysateLane 3 : NIH/3T3 cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat Anti-rabbit HRP

Anti-RALB Antibody (Glu142) - LS-C75330 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-RALB Antibody (C-Terminus, clone EPR6471) - LS-C154398 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6471
Western blot analysis on (A) HepG2, (B) 293T, and (C) NIH/3T3 cell lysates using anti-RALB antibody.

Anti-RALB Antibody - LS-C38719 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
WB analysis of rhRalA and rhRalB, and lysates of human U937 and rat Y3-Ag cells

Anti-RALB Antibody (aa89-183, Azide-free) - LS-C328469 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-RALB Antibody - LS-C341025 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RALB Antibody (aa107-156) - LS-C116643 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
RALB antibody LS-C116643 Western blot of ACHN lysate.

Anti-RALB Antibody (aa97-146) - LS-C170251 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-RALB Antibody (aa1-206) - LS-C186044 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (30 ug of whole cell lysate). A: Hep G2 . 12% SDS PAGE. RALB antibody diluted at 1:1000

Anti-RALB Antibody - LS-C334900 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using RALB antibody.

Anti-RALB Antibody (clone 4D1) IHC-plus™ - LS-B5523 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 4D1
Anti-RALB antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5523 concentration 5 ug/ml.

Anti-RALB Antibody (clone 2C4) - LS-C174563 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2C4
IHC of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-RALB mouse monoclonal antibody.
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