SPIC

Gene Symbol	SPIC
Entrez Gene	121599
Alt Symbol	SPI-C
Species	Human
Gene Type	protein-coding
Description	Spi-C transcription factor (Spi-1/PU.1 related)
Other Description	transcription factor Spi-C
Swissprots	Q8N5J4
Accessions	CCQ77680 EAW97662 Q8N5J4 AF518404 AAN84476 BC032317 AAH32317 EU446849 ABZ92378 XM_005268646 XP_005268703 XM_006719239 XP_006719302 NM_152323 NP_689536
Function	Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus {ECO:0000305}.
Tissue Specificity	Preferentially detected in fetal and adult spleen, lymph nodes and at lower levels in bone marrow and fetal liver. {ECO:0000269|PubMed:12459275}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Spic full length protein - ab165176 from Abcam Category Protein Source Wheat germ Species Human

SPIC Antibody Blocking Peptide - LS-E14487 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SPIC Antibody Blocking Peptide - LS-E14486 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SPIC Antibody Blocking Peptide - LS-E11263 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SPIC Antibody Blocking Peptide - LS-E13597 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human SPIC Protein - H00121599-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

SPIC Blocking Peptide - 33R-6533 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SPIC Blocking Peptide - 33R-5334 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SPIC - H00121599-P01-02 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Source in vitro transl. Species Human

SPIC fusion protein - ag4233 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Transcription factor Spi-C(SPIC) - CSB-YP818708HU CSB-EP818708HU CSB-BP818708HU CSB-MP818708HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

SPIC (full length, N-term HIS tag) - TP760153 from Acris Antibodies Category Protein Prices $199.00 Sizes 50 µg Source E. coli Species Human

SPIC-Antibody-Center-Blocking-peptide - BP10278c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SPIC Peptide, Human - M34GP15046H from Creative Peptides Category Peptide Source Synthetic. Species Human

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