DACH1

Gene Symbol	DACH1
Entrez Gene	1602
Alt Symbol	DACH
Species	Human
Gene Type	protein-coding
Description	dachshund family transcription factor 1
Other Description	dac homolog|dachshund homolog 1
Swissprots	Q96SG3 Q9H524 D0FY36 D0FY35 Q5VYY4 O75523 Q96SG4 O75687 Q5VYY3 Q9UMH4 Q9UI36
Accessions	EAW80508 EAW80509 EAW80510 EAW80511 EAW80512 Q9UI36 AA007235 AF069509 AAC33466 AF102546 AAF01351 AF356492 AAL08487 AJ005670 CAA06666 AK001000 AL079278 CAB45153 BC021219 AAH21219 BC166617 AAI66617 BM476209 BQ440916 BQ938052 BQ951567 XM_011534939 XP_011533241 XM_011534940 XP_011533242 XM_011534941 XP_011533243 XM_011534942 XP_011533244 NM_004392 NP_004383 NM_080759 NP_542937 NM_080760 NP_542938
Function	Transcription factor that is involved in regulation of organogenesis. Seems to be a regulator of SIX1, SIX6 and probably SIX5. Corepression of precursor cell proliferation in myoblasts by SIX1 is switched to coactivation through recruitment of EYA3 to the SIX1-DACH1 complex. Transcriptional activation seems also to involve association of CREBBP. Seems to act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin- dependent kinase inhibitors, including the p27Kip1 promoter (By similarity). Inhibits TGF-beta signaling through interaction with SMAD4 and NCOR1. Binds to chromatin DNA via its DACHbox-N domain (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:14525983}.
Tissue Specificity	Widely expressed. Isoform 2 is found in brain, heart, kidney, liver, leukocytes and spleen. Isoform 3 is found in liver and heart. Isoform 4 is found in spleen. {ECO:0000269|PubMed:11543628}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human DACH1 peptide - ab31586 from Abcam Category Peptide

Human DACH1 peptide - ab31587 from Abcam Category Peptide

Human DACH1 protein fragment - ab114777 from Abcam Category Protein Source Wheat germ Species Human

DACH / DACH1 Antibody Blocking Peptide - LS-E5219 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DACH / DACH1 Antibody Blocking Peptide - LS-E14434 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DACH / DACH1 Antibody Blocking Peptide - LS-E14435 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DACH1 Partial Recombinant Protein - H00001602-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

DACH1-Antibody-Center-Blocking-Peptide - BP17662c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DACH1 blocking peptide - GTX88629-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Pig, Rat

DACH1 Peptide - AC21-1499-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

DACH1 - H00001602-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

DACH1 - H00001602-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

DACH1 Peptide - 42-747P from ProSci Category Peptide Species Human

DACH1 fusion protein - ag1354 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

DACH1 fusion protein - Ag4474 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human DACH1 - DACH1-27091TH from Creative Biomart Category Protein Source Wheat germ Species Human

Recombinant Human Dachshund homolog 1(DACH1) - CSB-YP887059HU CSB-EP887059HU CSB-BP887059HU CSB-MP887059HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

DACH1 Protein - abx164248 from Abbexa Category Protein Species Human, Mouse, Rat

Dachshund homolog 1, Peptide - MBS426948 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog, Pig

DACH1 Recombinant Protein Antigen - NBP1-85320PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

DACH1 Peptide, Human - M34GP04008H from Creative Peptides Category Peptide Source Synthetic. Species Human

Dachshund homolog 1 (DACH1), Recombinant Protein - MBS1395294 from MyBioSource Category Protein Prices $1,575.00, $1,575.00, $1,805.00, $1,805.00, $2,715.00, $2,715.00, $3,155.00, $3,155.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Recombinant Human DACH1 Protein, GST-tagged - DACH1-2319H from Creative Biomart Category Protein Source Wheat Germ Species Human

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