MEOX2

Gene Symbol MEOX2
Entrez Gene 4223
Alt Symbol GAX, MOX2
Species Human
Gene Type protein-coding
Description mesenchyme homeobox 2
Other Description growth arrest-specific homeobox|homeobox protein MOX-2
Swissprots P50222 O75263 B2R8I7 Q9UPL6
Accessions AAC06184 AAC33152 EAL24289 EAW93666 P50222 AK309472 AK313386 BAG36184 BC017021 AAH17021 BQ025060 CR536553 CAG38790 DA586635 L36328 AAA58497 X82629 CAA57949 NM_005924 NP_005915
Function Mesodermal transcription factor that plays a key role in somitogenesis and is required for sclerotome development (By similarity). Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner (PubMed:22206000). May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle. {ECO:0000250|UniProtKB:P32443, ECO:0000269|PubMed:22206000}.
Subcellular Location Nucleus {ECO:0000269|PubMed:19266028, ECO:0000269|PubMed:22206000}. Nucleus speckle {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:19266028}.
Tissue Specificity Embryo and placenta.

MOX-2 (E-7) - sc-390537 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MOX-2 (E-7): sc-390537. Western blot analysis of MOX-2 expression in non-transfected: sc-110760 (A) and human MOX-2 transfected: sc-113256 (B) 293T whole cell lysates.

MOX-2 (A-8) - sc-376748 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MOX-2 (A-8): sc-376748. Western blot analysis of MOX-2 expression in non-transfected: sc-110760 (A) and human MOX-2 transfected: sc-113256 (B) 293 whole cell lysates.

MOX-2 (C-15) - sc-10189 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MOX-2 (C-15): sc-10189. Immunoperoxidase staining of formalin fixed, paraffin-embedded human placenta tissue showing nuclear and cytoplasmic staining of decidual cells.

MOX-2 (G-15) - sc-10187 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

MOX-2 (K-20) - sc-10188 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

MOX-2 (H-95) - sc-292632 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
MOX-2 (H-95): sc-292632. Western blot analysis of MOX-2 expression in HeLa (A), PC-12 (B), NIH/3T3 (C) and MCF7 (D) whole cell lysates.

MOX-2 (JJ-7) - sc-81971 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
MOX-2 (JJ-7): sc-81971. Western blot analysis of MOX-2 expression in non-transfected 293T: sc-117752 (A), mouse MOX-2 transfected 293T: sc-121725 (B) and HeLa (C) whole cell lysates.

MOX-2 (F-7) - sc-390075 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MOX-2 (F-7): sc-390075. Western blot analysis of MOX-2 expression in non-transfected: sc-110760 (A) and human MOX-2 transfected: sc-113256 (B) 293 whole cell lysates.

Anti-MEOX 2 antibody - ab55731 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
MEOX 2 antibody (ab55731) used in immunohistochemistry at 1ug/ml on formalin fixed and paraffin embedded human kidney.

Anti-MEOX 2 antibody - ab174116 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-MEOX 2 antibody (ab174116) at 1/100 dilution + MDA-MB453 cell line lysate at 35 µg

Anti-MEOX 2 antibody - ab65083 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MEOX 2 antibody (ab65083) at 1/500 dilutionLane 1 : Extracts from COLO205 cellsLane 2 : Extracts from COLO205 cells with immunising peptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-MEOX 2 antibody - ab55729 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-MEOX 2 antibody [6A5] - ab117551 from Abcam

Prices $464.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 6A5
Detection limit for recombinant proprietary tagged MEOX 2 is approximately 0.3ng/ml as a capture antibody (ab117551).

Anti-MEOX 2 antibody [EPR5568] - ab124876 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5568
All lanes : Anti-MEOX 2 antibody [EPR5568] (ab124876) at 1/10000 dilutionLane 1 : NIH3T3 cell lysateLane 2 : HeLa cell lysateLane 3 : MCF7 cell lysateLane 4 : 293T cell lysateLane 5 : JAR cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-GAX / MEOX2 Antibody - LS-C311384 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GAX / MEOX2 Antibody (Asn184) - LS-C176772 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of MOX-2 (N184) pAb in extracts from COLO205 cells.

Anti-GAX / MEOX2 Antibody (aa164-192) - LS-C158130 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Fluorescent image of NIH-3T3 cell stained with MEOX2 Antibody. NIH-3T3 cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.1%, 10 min), then incubated with MEOX2 primary antibody (1:25, 1 h at 37°C). For secondary antibody, Alexa Fluor 488 conjugated donkey anti-rabbit antibody (green) was used (1:400, 50 min at 37°C). Cytoplasmic actin was counterstained with Alexa Fluor 555 (red) conjugated Phalloidin (7units/ml, 1 h at 37°C). MEOX2 immunoreactivity is localized to Nucleus significantly.

Anti-GAX / MEOX2 Antibody (clone 4F6) - LS-C339673 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4F6
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MEOX2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MEOX2.

Anti-GAX / MEOX2 Antibody (Internal, clone EPR5568) IHC-plus™ - LS-B8024 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5568
Anti-GAX / MEOX2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8024 dilution 1:50.

Anti-GAX / MEOX2 Antibody (clone 6A5) IHC-plus™ - LS-B5472 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 6A5
Anti-MEOX2 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5472 concentration 5 ug/ml.

Anti-GAX / MEOX2 Antibody (N-Terminus) - LS-C30732 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
A: Marker, B: Transfected 293T Cell Lysate

Anti-GAX / MEOX2 Antibody (aa164-192, AP) - LS-C263007 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GAX / MEOX2 Antibody (aa164-192, FITC) - LS-C263010 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GAX / MEOX2 Antibody (aa164-192, APC) - LS-C263008 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GAX / MEOX2 Antibody (N-Terminus) - LS-C30733 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
A: Marker, B: Jurkat Cell Lysate
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