Gene Symbol | MEOX2 |
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Entrez Gene | 4223 |
Alt Symbol | GAX, MOX2 |
Species | Human |
Gene Type | protein-coding |
Description | mesenchyme homeobox 2 |
Other Description | growth arrest-specific homeobox|homeobox protein MOX-2 |
Swissprots | P50222 O75263 B2R8I7 Q9UPL6 |
Accessions | AAC06184 AAC33152 EAL24289 EAW93666 P50222 AK309472 AK313386 BAG36184 BC017021 AAH17021 BQ025060 CR536553 CAG38790 DA586635 L36328 AAA58497 X82629 CAA57949 NM_005924 NP_005915 |
Function | Mesodermal transcription factor that plays a key role in somitogenesis and is required for sclerotome development (By similarity). Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner (PubMed:22206000). May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle. {ECO:0000250|UniProtKB:P32443, ECO:0000269|PubMed:22206000}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:19266028, ECO:0000269|PubMed:22206000}. Nucleus speckle {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:19266028}. |
Tissue Specificity | Embryo and placenta. |
Mouse/Human/Rat GAX / MEOX2 ELISA Kit (Cell-Based ELISA) - LS-F3113 from LifeSpan Bioscience
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MEOX2 (Human) IP-WB Antibody Pair - H00004223-PW1 from Acris Antibodies
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MEOX2 Colorimetric Cell-Based ELISA - CB5904 from Assay Biotechnology
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mesenchyme homeobox 2, ELISA Kit - MBS9340390 from MyBioSource
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MEOX2 ELISA Kit - DEIA-XYA1203 from Creative Diagnostics
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Human MEOX2 ELISA Kit - E024190 from Biobool
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anti-MEOX2 antibody - ARG65817 from Arigo Biolaboratories
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Human Homeobox protein MOX-2 (MEOX2) ELISA Kit - AE33766HU from ARP American Research Products
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MEOX2 Colorimetric Cell-Based ELISA Kit - EKA50763 from Biomatik
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