Gene Symbol | MEOX2 |
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Entrez Gene | 4223 |
Alt Symbol | GAX, MOX2 |
Species | Human |
Gene Type | protein-coding |
Description | mesenchyme homeobox 2 |
Other Description | growth arrest-specific homeobox|homeobox protein MOX-2 |
Swissprots | P50222 O75263 B2R8I7 Q9UPL6 |
Accessions | AAC06184 AAC33152 EAL24289 EAW93666 P50222 AK309472 AK313386 BAG36184 BC017021 AAH17021 BQ025060 CR536553 CAG38790 DA586635 L36328 AAA58497 X82629 CAA57949 NM_005924 NP_005915 |
Function | Mesodermal transcription factor that plays a key role in somitogenesis and is required for sclerotome development (By similarity). Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner (PubMed:22206000). May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle. {ECO:0000250|UniProtKB:P32443, ECO:0000269|PubMed:22206000}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:19266028, ECO:0000269|PubMed:22206000}. Nucleus speckle {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:19266028}. |
Tissue Specificity | Embryo and placenta. |
Human MEOX 2 full length protein - ab114829 from Abcam
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Human MEOX2 protein fragment - ab167892 from Abcam
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GAX / MEOX2 Antibody Blocking Peptide - LS-E5846 from LifeSpan Bioscience
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GAX / MEOX2 Antibody Blocking Peptide - LS-E11492 from LifeSpan Bioscience
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GAX / MEOX2 Antibody Blocking Peptide - LS-E13934 from LifeSpan Bioscience
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MEOX 2 Recombinant Protein - H00004223-P01 from Novus Biologicals
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Recombinant Human MEOX 2 Protein - NBP2-23228 from Novus Biologicals
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MEOX2-Antibody-Center-Blocking-Peptide - BP18398c from Abgent, a WuXi AppTec company
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MEOX2 protein (His tag) - 80R-2899 from Fitzgerald
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MEOX2 Blocking Peptide - abx062930 from Abbexa
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MEOX2 (188-304, His-tag) - AR51018PU-N from Acris Antibodies
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MEOX2 (188-304, His-tag) - AR51018PU-S from Acris Antibodies
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MEOX2 - H00004223-P01 from Acris Antibodies
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MEOX2 - H00004223-P01-10 from Acris Antibodies
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MEOX2 - H00004223-P01-25 from Acris Antibodies
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MEOX2 - H00004223-Q01-10 from Acris Antibodies
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MEOX2 - H00004223-Q01-25 from Acris Antibodies
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MEOX2, 188-304aa, Human, His tag, E.coli - 01-P2194 from ARP American Research Products
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MEOX2 fusion protein - Ag3086 from Proteintech Group
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Recombinant Human MEOX2 - MEOX2-29604TH from Creative Biomart
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Recombinant Human mesenchyme homeobox 2, His-tagged - MEOX2-240H from Creative Biomart
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MEOX2 Blocking Peptide - CBP1736 from Cohesion Biosciences
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MOX-2 (N184) Peptide - BS2006P from Bioworld Technology
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Recombinant Human Homeobox protein MOX-2(MEOX2) - CSB-YP013696HU CSB-EP013696HU CSB-BP013696HU CSB-MP013696HU from Cusabio
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MEOX2, 188-304aa, Human, His tag, E.coli - ATGP2194 from ATGen
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