PCGF1

Gene Symbol PCGF1
Entrez Gene 84759
Alt Symbol 2010002K04Rik, NSPC1, RNF3A-2, RNF68
Species Human
Gene Type protein-coding
Description polycomb group ring finger 1
Other Description RING finger protein 68|nervous system Polycomb-1|polycomb group RING finger protein 1
Swissprots Q7Z506 Q9BSM1
Accessions EAW99632 EAW99633 Q9BSM1 AF087884 AAP97183 AK125742 AL049296 BC004952 AAH04952 BU602498 HQ447406 ADQ31892 XM_005264618 XP_005264675 NM_032673 NP_116062
Function Component of the Polycomb group (PcG) multiprotein BCOR complex, a complex required to maintain the transcriptionally repressive state of some genes, such as BCL6 and the cyclin- dependent kinase inhibitor, CDKN1A. Transcriptional repressor that may be targeted to the DNA by BCL6; this transcription repressor activity may be related to PKC signaling pathway. Represses CDKN1A expression by binding to its promoter, and this repression is dependent on the retinoic acid response element (RARE element). Promotes cell cycle progression and enhances cell proliferation as well. May have a positive role in tumor cell growth by down- regulating CDKN1A. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering c
Subcellular Location Nucleus {ECO:0000269|PubMed:15620699, ECO:0000269|PubMed:21282530}.
Tissue Specificity Ubiquitous. {ECO:0000269|PubMed:11287196}.
Top Pathways Signaling pathways regulating pluripotency of stem cells

PCGF1 (S-14) - sc-109391 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

PCGF1 (V-12) - sc-109392 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

PCGF1 (Y-18) - sc-109393 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-PCGF1 antibody - ab200109 from Abcam

Host Rabbit
Clonality Polyclonal
Anti-PCGF1 antibody (ab200109) at 1/1000 dilution + Mouse brain total cell extract

Anti-PCGF1 antibody [EPR13037(2)] - ab183499 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR13037(2)
All lanes : Anti-PCGF1 antibody [EPR13037(2)] (ab183499) at 1/20000 dilutionLane 1 : Human fetal brain lysateLane 2 : HeLa cell lysateLane 3 : MCF7 cell lysateLane 4 : Jurkat cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution

Anti-NSPC1 / PCGF1 Antibody (aa117-151) - LS-C344663 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of lysates from human brain, mouse brain, mouse cerebellum, rat brain tissue (from left to right) with PCGF1 Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20 ug per lane.

Anti-NSPC1 / PCGF1 Antibody (aa143-192) - LS-C116234 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PCGF1 antibody LS-C116234 Western blot of HepG2 cell lysate.

PCGF1 Antibody - NBP1-56961 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal

PCGF1 Antibody - NBP1-82767 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PCGF1 Antibody (RNL-4) - NBP1-42519 from Novus Biologicals

Prices $199.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone RNL-4

PCGF1 Antibody - H00084759-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: PCGF1 Antibody [H00084759-A01] - PCGF1 polyclonal antibody (A01), Lot # 051114JC01. Western Blot analysis of PCGF1 expression in Daoy.

PCGF1 Antibody - H00084759-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: PCGF1 Antibody [H00084759-D01P] - Analysis of PCGF1 expression in Jurkat.

PCGF1 Polyclonal Antibody - bs-4958R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PCGF1 Polyclonal Antibody - bs-5734R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded rat brain tissue labeled with Anti-PCGF1 Polyclonal Antibody, Unconjugated (bs-5734R) at 1:200 followed by conjugation to the secondary antibody and DAB staining

Anti-PCGF1 antibody produced in rabbit - SAB1401902 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Polyclonal Anti-PCGF1, antibody produced in rabbit, purified immunoglobulin: <B>Cat. No. SAB1401902</B>: Antibody concentration: 1.0 - 5.0 μg/mL. Specific band of ~30.35 kDa using Jurkat lysate.

Anti-PCGF1 antibody produced in rabbit - SAB2105511 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PCGF1: <B>Cat. No. SAB2105511</B>: PCGF1 in HepG2 cell lysates with PCGF1 antibody at 1.0 μg/mL.

PCGF1 antibody - middle region (ARP43370_P050) - ARP43370_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PCGF1-Antibody-Center - AP20960a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of lysates from human brain, mouse brain, mouse cerebellum, rat brain tissue (from left to right), using PCGF1 Antibody (Center)(Cat. #AP20960a). AP20960a was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.

PCGF1-Antibody-Center - AW5417 from Abgent, a WuXi AppTec company

Prices $110.00, $325.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PCGF1 Antibody (Center) at 1:1000 dilution Lane 1: human brain lysates Lane 2: mouse brain lysates Lane 3: mouse cerebellum lysates Lane 4: rat brain lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution Predicted band size : 30 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

PCGF1-Antibody-Center - AP21270c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Anti-PCGF1 Antibody (Center)at 1:2000 dilution + K562 whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 30 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

PCGF1 antibody, Internal - GTX46898 from GeneTex

Prices $299.00
Sizes 50 μg
Host Rabbit
Clonality Polyclonal
Anti-PCGF1 antibody, Internal used in Western blot. GTX46898

PCGF1 antibody - orb101340 from Biorbyt

Prices $255.00, $340.00
Sizes 100 μg, 200 μg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed and paraffin embedded rat brain tissue (Dilution at:1:200) using PCGF1 antibody

PCGF1 antibody - 70R-4454 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

PCGF1 / RNF68 antibody - H00084759-A01 from Acris Antibodies

Prices $300.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
PCGF1 polyclonal antibody (A01), Lot # 051114JC01. Western Blot analysis of PCGF1 expression in Daoy.

PCGF1 / RNF68 antibody - H00084759-D01P from Acris Antibodies

Prices $390.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot analysis of PCGF1 expression in transfected 293T cell line (H00084759-T03) by PCGF1 MaxPab polyclonal antibody. Lane 1: PCGF1 transfected lysate(29.20 KDa). Lane 2: Non-transfected lysate.
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