SETD1B

Gene Symbol SETD1B
Entrez Gene 23067
Alt Symbol KMT2G, Set1B
Species Human
Gene Type protein-coding
Description SET domain containing 1B
Other Description SET domain-containing protein 1B|hSET1B|histone-lysine N-methyltransferase SETD1B|lysine N-methyltransferase 2G
Swissprots F6MFW1 Q9UPS6
Accessions Q9UPS6 AB028999 BAA83028 AK000810 BC047909 BC080192 JF813787 AEG67286 XM_005253858 XP_005253915 XM_006719296 XP_006719359 XM_011538053 XP_011536355 NM_015048 NP_055863
Function Histone methyltransferase that specifically methylates 'Lys-4' of histone H3, when part of the SET1 histone methyltransferase (HMT) complex, but not if the neighboring 'Lys- 9' residue is already methylated. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. The non-overalpping localization with SETD1A suggests that SETD1A and SETD1B make non-redundant contributions to the epigenetic control of chromatin structure and gene expression. Specifically tri-methylates 'Lys-4' of histone H3 in vitro.
Subcellular Location Nucleus speckle {ECO:0000269|PubMed:17355966}. Chromosome {ECO:0000269|PubMed:17355966}. Note=Localizes to a largely non- overlapping set of euchromatic nuclear speckles with SETD1A, suggesting that SETD1A and SET1B each bind to a unique set of target genes.
Top Pathways Lysine degradation

Human SETD1B ELISA Kit - E097634 from Biobool

Category ELISA Kit

Histone-lysine N-methyltransferase SETD1B (SETD1B), ELISA Kit - MBS2610390 from MyBioSource

Category ELISA Kit
Prices $300.00, $475.00, $1,825.00, $3,425.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone-lysine N-methyltransferase SETD1B, ELISA Kit - MBS2603427 from MyBioSource

Category ELISA Kit
Prices $315.00, $490.00, $1,825.00, $3,425.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone-lysine N-methyltransferase SETD1B, ELISA Kit - MBS2608224 from MyBioSource

Category ELISA Kit
Prices $315.00, $490.00, $1,825.00, $3,425.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone-lysine N-methyltransferase SETD1B , ELISA Kit - MBS2604060 from MyBioSource

Category ELISA Kit
Prices $315.00, $490.00, $1,825.00, $3,425.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone-lysine N-methyltransferase SETD1B, ELISA Kit - MBS2608322 from MyBioSource

Category ELISA Kit
Prices $315.00, $490.00, $1,825.00, $3,425.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone-lysine N-methyltransferase SETD1B, ELISA Kit - MBS2603695 from MyBioSource

Category ELISA Kit
Prices $275.00, $420.00, $1,615.00, $2,880.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone-lysine N-methyltransferase SETD1B, ELISA Kit - MBS2607010 from MyBioSource

Category ELISA Kit
Prices $315.00, $490.00, $1,825.00, $3,425.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone-lysine N-methyltransferase SETD1B, ELISA Kit - MBS2607697 from MyBioSource

Category ELISA Kit
Prices $315.00, $490.00, $1,825.00, $3,425.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone-lysine N-methyltransferase SETD1B, ELISA Kit - MBS2605560 from MyBioSource

Category ELISA Kit
Prices $290.00, $450.00, $1,755.00, $3,150.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone-Lysine N-Methyltransferase SETD1B (SETD1B), ELISA Kit - MBS9903932 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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