UBP1

Gene Symbol	UBP1
Entrez Gene	7342
Alt Symbol	LBP-1B, LBP-1a, LBP1A, LBP1B
Species	Human
Gene Type	protein-coding
Description	upstream binding protein 1 (LBP-1a)
Other Description	transcription factor LBP-1|upstream-binding protein 1
Swissprots	Q9UD76 Q9H8V0 Q9NZI7 Q68CT0 Q9UD78 Q86Y57
Accessions	EAW64454 EAW64455 EAW64456 EAW64457 Q9NZI7 AF198487 AAF32274 AK023274 BAB14501 AK023278 BAG51180 AK023322 AK027177 AK293100 BAF85789 AK309430 AL133032 AL831847 BC047235 AAH47235 CR749798 CAH18658 DB131031 EU446907 ABZ92436 XM_011534077 XP_011532379 XR_940498 NM_001128160 NP_001121632 NM_001128161 NP_001121633 NM_014517 NP_055332
Function	Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box. {ECO:0000250, ECO:0000269|PubMed:10644752, ECO:0000269|PubMed:2006421, ECO:0000269|PubMed:8114710}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:8114710}.
Tissue Specificity	Expressed in adrenal tissue, JEG-3, NCI-H295A, Hep-G2 and HeLa cell lines. {ECO:0000269|PubMed:10644752}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

UBP1 293T Cell Transient Overexpression Lysate(Denatured) - H00007342-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

UBP1 293 Cell Lysate - 407169 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

UBP1 Overexpression Lysate (Denatured) - H00007342-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

UBP1 Overexpression Lysate (Native) - NBL1-17561 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

LBP1 (h): 293T Lysate - sc-369892 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

UBP1 Over-expression Lysate Product - GWB-25B8EE from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

UBP1 Overexpression Lysate (Native) - NBP2-09469 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

UBP1 Overexpression Lysate (Denatured) - H00007342-T02 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl

Panoply™ Human UBP1 Knockdown Stable Cell Line - CSC-DC016997 from Creative biogene Category Cell Line Species Human

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