Gene Symbol | UBP1 |
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Entrez Gene | 7342 |
Alt Symbol | LBP-1B, LBP-1a, LBP1A, LBP1B |
Species | Human |
Gene Type | protein-coding |
Description | upstream binding protein 1 (LBP-1a) |
Other Description | transcription factor LBP-1|upstream-binding protein 1 |
Swissprots | Q9UD76 Q9H8V0 Q9NZI7 Q68CT0 Q9UD78 Q86Y57 |
Accessions | EAW64454 EAW64455 EAW64456 EAW64457 Q9NZI7 AF198487 AAF32274 AK023274 BAB14501 AK023278 BAG51180 AK023322 AK027177 AK293100 BAF85789 AK309430 AL133032 AL831847 BC047235 AAH47235 CR749798 CAH18658 DB131031 EU446907 ABZ92436 XM_011534077 XP_011532379 XR_940498 NM_001128160 NP_001121632 NM_001128161 NP_001121633 NM_014517 NP_055332 |
Function | Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box. {ECO:0000250, ECO:0000269|PubMed:10644752, ECO:0000269|PubMed:2006421, ECO:0000269|PubMed:8114710}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:8114710}. |
Tissue Specificity | Expressed in adrenal tissue, JEG-3, NCI-H295A, Hep-G2 and HeLa cell lines. {ECO:0000269|PubMed:10644752}. |
Human Upstream Binding Protein 1 full length protein - ab159769 from Abcam
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UBP1 Antibody Blocking Peptide - LS-E2941 from LifeSpan Bioscience
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UBP1 Antibody Blocking Peptide - LS-E27255 from LifeSpan Bioscience
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UBP1 Antibody Blocking Peptide - LS-E11826 from LifeSpan Bioscience
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Recombinant Human UBP1 Protein - H00007342-P01 from Novus Biologicals
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UBP1-Antibody-Center-Blocking-peptide - BP14065c from Abgent, a WuXi AppTec company
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UBP1 blocking peptide - GTX88226-PEP from GeneTex
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Upstream Binding Protein 1 Peptide - AC21-2075-P from Abcore
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UBP1 / LBP1 - H00007342-P01-10 from Acris Antibodies
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UBP1 / LBP1 - H00007342-P01-25 from Acris Antibodies
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UBP1 Peptide - 42-297P from ProSci
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UBP1 fusion protein - ag5010 from Proteintech Group
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UBP1 fusion protein - Ag4830 from Proteintech Group
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Recombinant Human Upstream-binding protein 1(UBP1) - CSB-YP865191HU CSB-EP865191HU CSB-BP865191HU CSB-MP865191HU from Cusabio
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UBP1 / LBP1 (full length, N-term HIS tag, transcript variant 3) - TP760761 from Acris Antibodies
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UBP1, Peptide - MBS426272 from MyBioSource
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UBP1 Peptide, Human - M34GP16997H from Creative Peptides
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Recombinant Human UBP1 Protein, HIS-tagged - UBP1-051H from Creative Biomart
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