| Gene Symbol | UBP1 |
|---|---|
| Entrez Gene | 7342 |
| Alt Symbol | LBP-1B, LBP-1a, LBP1A, LBP1B |
| Species | Human |
| Gene Type | protein-coding |
| Description | upstream binding protein 1 (LBP-1a) |
| Other Description | transcription factor LBP-1|upstream-binding protein 1 |
| Swissprots | Q9UD76 Q9H8V0 Q9NZI7 Q68CT0 Q9UD78 Q86Y57 |
| Accessions | EAW64454 EAW64455 EAW64456 EAW64457 Q9NZI7 AF198487 AAF32274 AK023274 BAB14501 AK023278 BAG51180 AK023322 AK027177 AK293100 BAF85789 AK309430 AL133032 AL831847 BC047235 AAH47235 CR749798 CAH18658 DB131031 EU446907 ABZ92436 XM_011534077 XP_011532379 XR_940498 NM_001128160 NP_001121632 NM_001128161 NP_001121633 NM_014517 NP_055332 |
| Function | Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box. {ECO:0000250, ECO:0000269|PubMed:10644752, ECO:0000269|PubMed:2006421, ECO:0000269|PubMed:8114710}. |
| Subcellular Location | Nucleus {ECO:0000269|PubMed:8114710}. |
| Tissue Specificity | Expressed in adrenal tissue, JEG-3, NCI-H295A, Hep-G2 and HeLa cell lines. {ECO:0000269|PubMed:10644752}. |
Human UBP1 cDNA clone(NM_001128161.1) - CDFH020777 from Creative Biomart
|
||||
Human UBP1 cDNA clone(NM_001128160.1) - CDFH020778 from Creative Biomart
|
||||
Human UBP1 ORF clone(NM_014517.4) - CDCR008352 from Creative Biomart
|
||||
human UBP1 ORF clone - CDCH097646 from Creative Biomart |
||||
human UBP1 ORF clone - CDCH097647 from Creative Biomart
|
||||
human UBP1 ORF clone - CDCH097648 from Creative Biomart
|
||||
human UBP1 ORF clone - CDCH097649 from Creative Biomart
|
||||
Human UBP1 ORF Clone(NM_001128160.1) - CDCR348955 from Creative Biomart
|
||||
Human UBP1 ORF Clone(NM_001128160.1) - CDCR348956 from Creative Biomart
|
||||
Human UBP1 ORF Clone(NM_001128161.1) - CDCR348958 from Creative Biomart
|
||||
Human UBP1 ORF Clone(NM_001128161.1) - CDCR348964 from Creative Biomart
|
||||
Human UBP1 ORF clone(NM_014517.4) - CDCR008352 from Creative biogene
|
||||
Human UBP1 ORF Clone(NM_001128161.1) - CDCR348958 from Creative biogene
|
||||
human UBP1 ORF clone (NM_001128160.1) - CDCH097648 from Creative biogene
|
||||
Human UBP1 cDNA Clone(NM_001128161.1) - CDFH020777 from Creative biogene
|
||||
Human UBP1 cDNA Clone(NM_001128160.1) - CDFH020778 from Creative biogene
|