RITA1

Gene Symbol	RITA1
Entrez Gene	84934
Alt Symbol	C12orf52, RITA
Species	Human
Gene Type	protein-coding
Description	RBPJ interacting and tubulin associated 1
Other Description	RBPJ-interacting and tubulin-associated protein 1
Swissprots	C9JIN1 Q53GM3 B3KVZ4 Q96K30 Q96K25 F8VRG5
Accessions	CAC32398 CAE90924 EAW98041 EAW98042 Q96K30 AA594422 AK027733 BAB55328 AK027741 BAB55333 AK075358 BAC11568 AK123762 BAG53956 AK222908 BAD96628 AY007158 BC022092 AAH22092 BP212183 BX366456 DA207985 HQ447411 ADQ31897 XM_005253972 XP_005254029 NM_001286215 NP_001273144 NM_032848 NP_116237
Function	Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis. {ECO:0000269|PubMed:21102556}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:21102556}. Nucleus {ECO:0000269|PubMed:21102556}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:21102556}. Note=Shuttles rapidly between the cytoplasm and the nucleus. The function of centrosome localization is still unclear.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

RITA1 / C12orf52 Antibody Blocking Peptide - LS-E1661 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CL052-Antibody-N-term-Blocking-peptide - BP12423a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human RBPJ-interacting and tubulin-associated protein(RITA) - CSB-YP842696HU CSB-EP842696HU CSB-BP842696HU CSB-MP842696HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Chromosome 12 open reading frame 52 (C12orf52) - TP301409 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

RITA Recombinant Protein Antigen - NBP1-94003PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

RITA Protein - NBP2-38441PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

C12ORF52 Peptide, Human - M34GP01690H from Creative Peptides Category Peptide Source Synthetic. Species Human

RBPJ-interacting and tubulin-associated protein (RITA), Recombinant Protein - MBS1464310 from MyBioSource Category Protein Prices $1,020.00, $1,020.00, $1,250.00, $1,250.00, $1,575.00, $1,575.00, $2,040.00, $2,040.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

RITA Recombinant Protein Antigen - NBP2-56524PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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