RITA1

Gene Symbol RITA1
Entrez Gene 84934
Alt Symbol C12orf52, RITA
Species Human
Gene Type protein-coding
Description RBPJ interacting and tubulin associated 1
Other Description RBPJ-interacting and tubulin-associated protein 1
Swissprots C9JIN1 Q53GM3 B3KVZ4 Q96K30 Q96K25 F8VRG5
Accessions CAC32398 CAE90924 EAW98041 EAW98042 Q96K30 AA594422 AK027733 BAB55328 AK027741 BAB55333 AK075358 BAC11568 AK123762 BAG53956 AK222908 BAD96628 AY007158 BC022092 AAH22092 BP212183 BX366456 DA207985 HQ447411 ADQ31897 XM_005253972 XP_005254029 NM_001286215 NP_001273144 NM_032848 NP_116237
Function Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis. {ECO:0000269|PubMed:21102556}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:21102556}. Nucleus {ECO:0000269|PubMed:21102556}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:21102556}. Note=Shuttles rapidly between the cytoplasm and the nucleus. The function of centrosome localization is still unclear.

C12orf52 CRISPR/Cas9 KO Plasmid (h) - sc-413739 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

C12orf52 HDR Plasmid (h) - sc-413739-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C12orf52 Double Nickase Plasmid (h) - sc-413739-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C12orf52 Double Nickase Plasmid (h2) - sc-413739-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C12orf52 CRISPR Activation Plasmid (h) - sc-413739-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

C12orf52 CRISPR Activation Plasmid (h2) - sc-413739-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

C12orf52 Lentiviral Activation Particles (h) - sc-413739-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C12orf52 Lentiviral Activation Particles (h2) - sc-413739-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C12orf52 siRNA (h) - sc-95782 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

C12orf52 shRNA Plasmid (h) - sc-95782-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

C12orf52 shRNA (h) Lentiviral Particles - sc-95782-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU146541 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN4263 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4263 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04206 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr04206

RITA1 siRNA (Human) - CRJ3705 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RITA1 - MBS8210741 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human C12orf52 (NM_032848.1) - SHH249138 from Creative biogene

Category siRNA
Species Reactivities Human

Human RITA1 siRNA - orb274206 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RITA1 shRNA Plasmid (Human) - CHJ3705 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

C12ORF52 miRNA 3'UTR clone - MiUTR1H-01069 from Creative biogene

Species Reactivities Human
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