Gene Symbol | GAS6 |
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Entrez Gene | 2621 |
Alt Symbol | AXLLG, AXSF |
Species | Human |
Gene Type | protein-coding |
Description | growth arrest-specific 6 |
Other Description | AXL receptor tyrosine kinase ligand|AXL stimulatory factor|growth arrest-specific protein 6 |
Swissprots | E9PBL7 Q6IMN1 B3KVL4 B3KRQ7 Q7Z7N3 Q14393 |
Accessions | AAO41859 AAO84057 ABR09277 DAA01155 EAX09226 Q14393 AA045119 AK092028 BAG52469 AK122969 BAG53826 AK126533 BAC86580 AK129751 AK290803 BAF83492 AK303145 BAG64249 AL833761 CAH56234 BC030708 BC038984 AAH38984 BQ181504 BX380508 DB290970 HY038614 L13720 AAA58494 NM_000820 NP_000811 NM_001143945 NM_001143946 |
Function | Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses. {ECO:0000269|PubMed:12364394, ECO:0000269|PubMed:18840707}. |
Subcellular Location | Secreted {ECO:0000269|PubMed:9326369}. |
Tissue Specificity | Plasma. Isoform 1 and isoform 2 are widely expressed. Isoform 1 is the predominant form in spleen. {ECO:0000269|PubMed:8336730, ECO:0000269|PubMed:9326368}. |
Gas6 (A-9) - sc-376087 from Santa Cruz Biotechnology
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Gas6 (D-18) - sc-16660 from Santa Cruz Biotechnology
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Gas6 (C-20) - sc-1935 from Santa Cruz Biotechnology
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Gas6 (H-140) - sc-22759 from Santa Cruz Biotechnology
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Gas6 (N-20) - sc-1936 from Santa Cruz Biotechnology
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Anti-GAS 6 antibody - ab136249 from Abcam
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Anti-GAS 6 antibody - ab198027 from Abcam
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Anti-GAS 6 antibody - ab85388 from Abcam
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Anti-GAS 6 antibody - ab67099 from Abcam
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Anti-GAS 6 antibody [MM0302-4X13] - ab89561 from Abcam
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Anti-GAS6 Antibody (aa260-309) - LS-C291977 from LifeSpan Bioscience
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Anti-GAS6 Antibody - LS-C294340 from LifeSpan Bioscience
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Anti-GAS6 Antibody (aa136-311, Biotin) - LS-C299203 from LifeSpan Bioscience
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Anti-GAS6 Antibody (aa59-221, Biotin) - LS-C299537 from LifeSpan Bioscience
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Anti-GAS6 Antibody (aa59-221, FITC) - LS-C303892 from LifeSpan Bioscience
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Anti-GAS6 Antibody (aa136-311, FITC) - LS-C304935 from LifeSpan Bioscience
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Anti-GAS6 Antibody (FITC) - LS-C303470 from LifeSpan Bioscience
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Anti-GAS6 Antibody - LS-C308307 from LifeSpan Bioscience
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Anti-GAS6 Antibody - LS-C310459 from LifeSpan Bioscience
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Anti-GAS6 Antibody (aa136-311) - LS-C294339 from LifeSpan Bioscience
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Anti-GAS6 Antibody (aa59-221) - LS-C294341 from LifeSpan Bioscience
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Anti-GAS6 Antibody (aa291-340) - LS-C119038 from LifeSpan Bioscience
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Anti-GAS6 Antibody (Gly309) - LS-C177065 from LifeSpan Bioscience
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Gas6 Antibody - AF885 from Novus Biologicals
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Gas6 Antibody - AB885 from Novus Biologicals
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