Bcl2

Gene Symbol Bcl2
Entrez Gene 12043
Alt Symbol AW986256, Bcl-2, C430015F12Rik, D630044D05Rik, D830018M01Rik
Species Mouse
Gene Type protein-coding
Description B cell leukemia/lymphoma 2
Other Description B-cell leukemia/lymphoma 2|apoptosis regulator Bcl-2
Swissprots P10417 Q4VBF6 P10418
Accessions AAA37281 AAA37282 EDL39861 EDL39862 P10417 AA867214 AK042257 AK049473 BAC33767 AK052879 AK076269 AK077913 AK155394 AK200702 AK219312 BB612176 BB662051 BC068988 AAH68988 BC095964 AAH95964 BQ887357 CD741269 CF736820 CJ106885 CJ161448 NM_009741 NP_033871 NM_177410 NP_803129
Function Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
Subcellular Location Mitochondrion outer membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Tissue Specificity Expressed in a variety of tissues.
Top Pathways Toxoplasmosis, MicroRNAs in cancer, Epstein-Barr virus infection, Adrenergic signaling in cardiomyocytes, Sphingolipid signaling pathway

Bcl-2 (4C11) - sc-578 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal
Bcl-2 (4C11): sc-578. Immunofluorescence staining of methanol-fixed NIH/3T3 cells showing cytoplasmic localization.

Bcl-2 (10C4) - sc-23960 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Bcl-2 (10C4): sc-23960. Western blot analysis of Bcl-2 expression in WEHI-231 whole cell lysate (A) and mouse spleen (B) and rat spleen (C) tissue extracts.

Bcl-2 (YTH10C4) - sc-81002 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Bcl-2 (YTH10C4): sc-81002. Western blot analysis of Bcl-2 expression in non-transfected: sc-117752 (A) and mouse Bcl-2 transfected: sc-118779 (B) 293T whole cell lysates.

Bcl-2 (5K140) - sc-70411 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Bcl-2 (5K140): sc-70411. Western blot analysis of Bcl-2 expression in non-transfected: sc-117752 (A) and mouse Bcl-2 transfected: sc-118779 (B) 293T whole cell lysates.

Bcl-2 Antibody (BCL/10C4) - NB100-78543 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone BCL/10C4
Western Blot: Bcl-2 Antibody (BCL/10C4) [NB100-78543] - Analysis of extracts from mouse splenocytes using anti-Bcl-2, clone BCL/10C4.

Bcl-2 Antibody (BCL/10C4) [DyLight 405LS] - NB100-78543V3 from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone BCL/10C4

Bcl-2 Antibody (BCL/10C4) [DyLight 755] - NB100-78543IR from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone BCL/10C4

Bcl-2 Antibody (BCL/10C4) [DyLight 680] - NB100-78543FR from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone BCL/10C4

Bcl-2 Antibody (BCL/10C4) [Allophycocyanin] - NB100-78543APC from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone BCL/10C4

Bcl-2 Antibody (BCL/10C4) [PerCP] - NB100-78543PCP from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone BCL/10C4

Bcl-2 Antibody (BCL/10C4) [PE] - NB100-78543PE from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone BCL/10C4

Bcl-2 Antibody (BCL/10C4) [DyLight 488] - NB100-78543G from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone BCL/10C4

Bcl-2 Antibody (BCL/10C4) [7C] - NB100-78543V2 from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone BCL/10C4

Bcl-2 Antibody (BCL/10C4) [DyLight 405] - NB100-78543V from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone BCL/10C4

Bcl-2 Antibody (BCL/10C4) [DyLight 350] - NB100-78543UV from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone BCL/10C4

Bcl-2 Antibody (BCL/10C4) [Alexa Fluor (R) 700] - NB100-78543AF700 from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone BCL/10C4

Bcl-2 Antibody (BCL/10C4) [Alexa Fluor (R) 647] - NB100-78543AF647 from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone BCL/10C4

Bcl-2 Antibody (BCL/10C4) [Alexa Fluor (R) 488] - NB100-78543AF488 from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone BCL/10C4

Bcl-2 Antibody (BCL/10C4) [Alexa Fluor (R) 405] - NB100-78543AF405 from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone BCL/10C4

Monoclonal Anti-Bcl-2 antibody produced in mouse - B9804 from Sigma-Aldrich

Prices $347.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone 10C4

Anti -BCL2 (Apoptosis Regulator Bcl-2) - B0003-46E1 from USBiological Life Science

Host Mouse
Clonality Monoclonal

Anti -BCL2 (Apoptosis Regulator Bcl-2, B Cell CLL/lymphoma 2) - 139390 from USBiological Life Science

Host Rabbit
Clonality Polyclonal

Anti -BCL2 (Apoptosis Regulator Bcl-2, B Cell CLL/lymphoma 2) (AP) - 139390-AP from USBiological Life Science

Host Rabbit
Clonality Polyclonal

Anti -BCL2 (Apoptosis Regulator Bcl-2, B Cell CLL/lymphoma 2) (APC) - 139390-APC from USBiological Life Science

Host Rabbit
Clonality Polyclonal

Anti -BCL2 (Apoptosis Regulator Bcl-2, B Cell CLL/lymphoma 2) (Biotin) - 139390-Biotin from USBiological Life Science

Host Rabbit
Clonality Polyclonal
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