Bcl2

Gene Symbol Bcl2
Entrez Gene 12043
Alt Symbol AW986256, Bcl-2, C430015F12Rik, D630044D05Rik, D830018M01Rik
Species Mouse
Gene Type protein-coding
Description B cell leukemia/lymphoma 2
Other Description B-cell leukemia/lymphoma 2|apoptosis regulator Bcl-2
Swissprots P10417 Q4VBF6 P10418
Accessions AAA37281 AAA37282 EDL39861 EDL39862 P10417 AA867214 AK042257 AK049473 BAC33767 AK052879 AK076269 AK077913 AK155394 AK200702 AK219312 BB612176 BB662051 BC068988 AAH68988 BC095964 AAH95964 BQ887357 CD741269 CF736820 CJ106885 CJ161448 NM_009741 NP_033871 NM_177410 NP_803129
Function Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
Subcellular Location Mitochondrion outer membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Tissue Specificity Expressed in a variety of tissues.
Top Pathways Toxoplasmosis, MicroRNAs in cancer, Epstein-Barr virus infection, Adrenergic signaling in cardiomyocytes, Sphingolipid signaling pathway

Bcl-2 CRISPR/Cas9 KO Plasmid (m) - sc-419304 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Bcl-2 HDR Plasmid (m) - sc-419304-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Bcl-2 Double Nickase Plasmid (m) - sc-419304-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Bcl-2 Double Nickase Plasmid (m2) - sc-419304-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Bcl-2 CRISPR Activation Plasmid (m) - sc-419304-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Bcl-2 CRISPR Activation Plasmid (m2) - sc-419304-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Bcl-2 Lentiviral Activation Particles (m) - sc-419304-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Bcl-2 Lentiviral Activation Particles (m2) - sc-419304-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Bcl-2 siRNA (m) - sc-29215 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

Bcl-2 shRNA Plasmid (m) - sc-29215-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

Bcl-2 shRNA (m) Lentiviral Particles - sc-29215-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MISSION® esiRNA - EMU037461 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN27555 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND27555 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

BCL2 siRNA (Mouse) - CRM0356 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

BCL2 - MBS8209977 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse BCL2 (NM_009741.3) - SHH245886 from Creative biogene

Category siRNA
Species Reactivities Mouse

Mouse BCL2 siRNA - orb279832 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

BCL2 shRNA Plasmid (Mouse) - CHM0356 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse

BCL2 miRNA 3'UTR clone - MiUTR1M-02155 from Creative biogene

Species Reactivities Mouse

BCL2 miRNA 3'UTR clone - MiUTR1M-02156 from Creative biogene

Species Reactivities Mouse
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