Bcl2

Gene Symbol	Bcl2
Entrez Gene	12043
Alt Symbol	AW986256, Bcl-2, C430015F12Rik, D630044D05Rik, D830018M01Rik
Species	Mouse
Gene Type	protein-coding
Description	B cell leukemia/lymphoma 2
Other Description	B-cell leukemia/lymphoma 2|apoptosis regulator Bcl-2
Swissprots	P10417 Q4VBF6 P10418
Accessions	AAA37281 AAA37282 EDL39861 EDL39862 P10417 AA867214 AK042257 AK049473 BAC33767 AK052879 AK076269 AK077913 AK155394 AK200702 AK219312 BB612176 BB662051 BC068988 AAH68988 BC095964 AAH95964 BQ887357 CD741269 CF736820 CJ106885 CJ161448 NM_009741 NP_033871 NM_177410 NP_803129
Function	Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
Subcellular Location	Mitochondrion outer membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Tissue Specificity	Expressed in a variety of tissues.
Top Pathways	Toxoplasmosis, MicroRNAs in cancer, Epstein-Barr virus infection, Adrenergic signaling in cardiomyocytes, Sphingolipid signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse Bcl2 ORF Clone(NM_009741.3) - CDCR247770 from Creative biogene Species Mouse

Mouse Bcl2 ORF Clone(NM_177410.2) - CDCR273932 from Creative biogene Species Mouse

Mouse Bcl2 cDNA Clone(NM_177410.2) - CDFL001849 from Creative biogene Species Mouse

Mouse BCL2/Bcl-2 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - MG53719-ANG from Sino Biological Species Mouse

Mouse BCL2/Bcl-2 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - MG53719-ANR from Sino Biological Species Mouse

Mouse BCL2/Bcl-2 Gene ORF cDNA clone expression plasmid, C-Flag tag - MG53719-CF from Sino Biological Species Mouse

Mouse BCL2/Bcl-2 Gene ORF cDNA clone expression plasmid, C-His tag - MG53719-CH from Sino Biological Species Mouse

Mouse BCL2/Bcl-2 Gene ORF cDNA clone expression plasmid, C-Myc tag - MG53719-CM from Sino Biological Species Mouse

Mouse BCL2/Bcl-2 Gene ORF cDNA clone expression plasmid, C-HA tag - MG53719-CY from Sino Biological Species Mouse

Mouse BCL2/Bcl-2 Gene ORF cDNA clone expression plasmid, N-Flag tag - MG53719-NF from Sino Biological Species Mouse

Mouse BCL2/Bcl-2 Gene ORF cDNA clone expression plasmid, N-His tag - MG53719-NH from Sino Biological Species Mouse

Mouse BCL2/Bcl-2 Gene ORF cDNA clone expression plasmid, N-Myc tag - MG53719-NM from Sino Biological Species Mouse

Mouse BCL2/Bcl-2 Gene ORF cDNA clone expression plasmid, N-HA tag - MG53719-NY from Sino Biological Species Mouse

Mouse BCL2/Bcl-2 Gene ORF cDNA clone in cloning vector - MG53719-U from Sino Biological Species Mouse

Mouse BCL2/Bcl-2 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - MG53719-ACR from Sino Biological Species Mouse

Mouse BCL2/Bcl-2 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - MG53719-ACG from Sino Biological Species Mouse

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