Bcl2

Gene Symbol	Bcl2
Entrez Gene	12043
Alt Symbol	AW986256, Bcl-2, C430015F12Rik, D630044D05Rik, D830018M01Rik
Species	Mouse
Gene Type	protein-coding
Description	B cell leukemia/lymphoma 2
Other Description	B-cell leukemia/lymphoma 2|apoptosis regulator Bcl-2
Swissprots	P10417 Q4VBF6 P10418
Accessions	AAA37281 AAA37282 EDL39861 EDL39862 P10417 AA867214 AK042257 AK049473 BAC33767 AK052879 AK076269 AK077913 AK155394 AK200702 AK219312 BB612176 BB662051 BC068988 AAH68988 BC095964 AAH95964 BQ887357 CD741269 CF736820 CJ106885 CJ161448 NM_009741 NP_033871 NM_177410 NP_803129
Function	Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
Subcellular Location	Mitochondrion outer membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Tissue Specificity	Expressed in a variety of tissues.
Top Pathways	Toxoplasmosis, MicroRNAs in cancer, Epstein-Barr virus infection, Adrenergic signaling in cardiomyocytes, Sphingolipid signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Recombinant Mouse Apoptosis regulator Bcl-2 protein (OPCA00023) - OPCA00023 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Mouse

Mouse Bcl2 Bcl-2 protein - orb244042 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Mouse

Mouse BCL2 protein - orb197616 from Biorbyt Category Protein Prices $391.00, $519.00 Sizes 50 μg, 100 μg Species Mouse

Mouse Bcl2 Protein - abx065514 from Abbexa Category Protein Source E.coli Species Mouse

B-Cell Leukemia/Lymphoma 2 (Bcl2), Mouse - 20-7092 from ARP American Research Products Category Protein Prices $419.00 Sizes 50 µg Source E.coli Species Mouse

Recombinant Mouse Bcl2, His-tagged - Bcl2-3582M from Creative Biomart Category Protein Source E. Coli or Yeast Species Mouse

Recombinant B-Cell Leukemia/Lymphoma 2 (Bcl2) - RPA778Mu01 from Cloud-clone Category Protein Source E.coli Species Mouse

Recombinant B-Cell Leukemia/Lymphoma 2 (Bcl2) - RPA778Mu02 from Cloud-clone Category Protein Source E.coli Species Mouse

Recombinant mouse Apoptosis regulator Bcl-2 protein - CSB-EP002611MO CSB-BP002611MO CSB-MP002611MO from Cusabio Category Protein Source E.coli or Baculovirus or Mammalian cell Species Mouse

Recombinant mouse Apoptosis regulator Bcl-2 protein - CSB-YP002611MO from Cusabio Category Protein Source E.coli Species Mouse

Apoptosis regulator Bcl-2 protein - RPC140183 from Biomatik Category Protein Prices $299.20, $352.00, $550.00, $687.50, $997.50, $1,507.50 Sizes 10 µg, 50 µg, 100 µg, 200 µg, 500 µg, 1 mg Source E.coli Species Mouse

B-Cell Leukemia/Lymphoma 2 (Bcl2) - RPU140438 from Biomatik Category Protein Prices $192.50, $385.00, $577.50 Sizes 10 µg, 50 µg, 100 µg Source E.coli Species Mouse

Apoptosis regulator Bcl-2 (Bcl2), Recombinant Protein - MBS718098 from MyBioSource Category Protein Prices $1,460.00, $1,915.00 Sizes 1 mg (E-Coli), 1 mg (Yeast) Source E Coli or Yeast Species Mouse

Recombinant Mouse BCL2 Protein - BCL2-2337M from Creative Biomart Category Protein Source Mammalian Cells Species Mouse

Bcl2 fusion protein - Ag24260 from Proteintech Group Category Protein Source E. coli -derived, PGEX-4T Species Mouse

BCL2 (pS70) Blocking Peptide - CBP7145 from Cohesion Biosciences Category Peptide Prices $150.00, $450.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

Recombinant Mouse Apoptosis regulator Bcl-2(Bcl2),partial - CSB-EP002611MO from Cusabio Category Protein Source E.coli Species Mouse

Recombinant B-Cell Leukemia/Lymphoma 2 (Bcl2) - RPU40438 from Biomatik Category Protein Prices $182.00, $315.00, $482.00, $602.00 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Mouse

BCL2 Recombinant Protein (OPCD01600) - OPCD01600 from Aviva Systems Biology Category Protein Source E.coli Species Mouse

Recombinant mouse Apoptosis regulator Bcl-2 protein - AP70076 from Signalway Antibody Category Protein Prices $260.00, $735.00, $1,240.00, $1,975.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source E.coli Species Mouse

B-Cell Leukemia/Lymphoma 2 (Bcl2), Recombinant Protein - MBS2011595 from MyBioSource Category Protein Prices $160.00, $320.00, $495.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Mouse

BCL2 Recombinant Protein (Mouse) (OPCA03805) - OPCA03805 from Aviva Systems Biology Category Protein Species Mouse

Recombinant Mouse BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 (Bnip3), partial - RPC20988 from Biomatik Category Protein Prices $276.00, $505.00, $2,491.00 Sizes 50 µg, 100 µg, 1 mg Source E.coli Species Mouse

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